232 PKINCIPLES OF STOCK-BREEDING. 



and a female branch of the same family, as in the 

 following case, related by F. Meckel " (Lancet, 1829 

 -'30, vol. i., page 792), "in which the modified in- 

 fluence of sex is associated with atavism of unequal 

 remoteness ; ' a man whose palate was entire, but un- 

 even, as if cicatrized, had, by a perfectly healthy wife, 

 seven children, of whom the four boys were well 

 formed, but the three girls had hare-lip and divided 

 palate. His mother's sister had also seven children, 

 five sons and two daughters, of whom the former 

 were all similarly deformed.' " * 



In the two following cases, the one of a disease 

 and the other of a congenital defect of the male organs 

 of generation, the female parent transmits to her off- 

 spring peculiarities that she could not herself be af- 

 fected with. 



Sir Henry Holland reports a case " of hydrocele 

 occurring in three out of four generations in one fam- 

 ily, the omission adding to the singularity of the fact 

 from its depending on a female being third in the 

 series, in whose son the complaint reappeared." a 



Many cases of hereditary hypospadias (a defect of 

 the male urethra) are on record. 



" In a case observed by Meckel, it appears that a 

 woman, born of a family which presented many ex- 

 amples of hypospadias, gave birth to two boys affected 

 with the deformity." 8 



1 British and Foreign Medico- Chirurgical Review, July, 1863, p. 193. 



* Edinburgh Medical Journal, 1858-'59, p. 501 ; quoted in British 

 and Foreign Medico- Chirurgical Review, July, 1861, p. 148. 



8 British and Foreign Medico-Chirurgical Review, July, 1863, p. 

 173. 



