SARCODINA 



ENDAMEBA HISTOLYTICA 



725 



(Endameba tetragena [Viereck], Endameba africana [Hartmann], 



Endamcba nipponica [Koidzumi, pro parte], Endameba 



tropicalis [Lesage, pro parte] ) 



Amebae as a cause of disease were first described by Lambl of 

 Prague, in 1860, who found them present in the stools from a case 

 of severe diarrhea in a child. In 1870 Lewis and Cunningham found 

 amebae in 20 per cent of the stools of cholera patients, but attached no 

 pathogenic importance to them. The first accurate description we owe 

 to Loesch of Petrograd, who in 1875 studied an undoubted case of 



i IG. 157. ENDAMEBA HISTOLYTICA. Vegetative form, simple division. Tetragena 

 type of nucleus. (X 1300.) (Army Medical School Collection, Washington, D. C.) 



amebic dysentery with relapses, and he named the organism Ameba 

 coli. He was further successful in reproducing the disease in a dog, 

 and thus began its experimental investigation. Not much progress 

 was made until Kartulis in Egypt began, in 1886, the publication of 

 a long series of studies which has continued up to the present time, 

 and because of the rich clinical and pathological material at his dis- 

 posal his work has been of the greatest value. In 1890 Osier published 

 the first paper in America. He was followed by Musser and Stengel 

 and, in 1891, by Dock, and Councilman and Lafleur. The work of the 



