- 5 8- 



icodendrol" as the name of the poisonous principle. The poison- 

 ous principle of Japanese lac is so intimately associated with the 

 resin of the lac that I have not considered the method of fraction- 

 al precipitation to be a complete separation. Preceding investiga- 

 tions indicate that the poisonous principles of these plants are 

 identical but further investigation is necessary before this can be 

 accepted as conclusive. I hope during the coming year to be able 

 to separate the poison from both these plants and to determine 

 their relation. 



The present researches in Japanese Lac were undertaken in 

 the Laboratory of the Pharmaceutical Institute of Bern under 

 the guidance of my most highly esteemed director, Professor A. 

 Tschirch. To him and also to Professor Oesterle I desire to ex- 

 press my warmest and sincerest thanks for the inspiration and 

 the friendly interest and advice which has ever been so freely 

 and so kindly given. 



I am also thankful to Dr. Jadassohn and his assistants, Drs. 

 Winckler and Schulz for the physiological tests which they so 

 kindly made. 



The lac for this investigation was kindly presented by fores- 

 ter Shirasawa of Tokio, Japan, and the Rhus Company, Frank- 

 fort, Germany. To them I extend sincere thanks. 



OF THE 



UNIVERSITY 



