56 HEALTH AND DISEASE 



such districts, are carefully inspected and their temperature taken daily, 

 the first symptoms discovered will be fever about the seventh or eighth 

 day after infection ; and if my memory serves me correctly, when investi- 

 gating this disease under the supervision of Dr. Edington, the incubation 

 periods in animals experimentally inoculated was from six to eight days. 

 A noteworthy feature about the temperature is that it gradually rises, 

 and seldom, if ever, is below the previous day's temperature, taken at 

 the same time. The morning and evening temperature will be higher 

 than that of the previous day, although the morning temperature may 

 be below that of the previous evening, but will be higher than that of 

 the previous morning, and so gradually increases to 105°, and in some 

 cases to 107° Fahrenheit, until the final stage is reached, when it suddenly 

 drops to normal or below it. 



" The primary rise of temperature is soon followed by a dusky-yellow 

 pinkish discoloration of the conjunctiva, which is congested, and invari- 

 ably petechial or stellate spots are present, which are always well marked ; 

 and generally there is a watery discharge from the eyes, and a peculiar 

 dry husky breathing can be detected on auscultation at the trachea. In 

 a day or two these symptoms become more marked, and are followed 

 by oedema of the conjunctiva and eyelids, swelling of the orbital fossa, 

 injection of the nasal mucous membranes, swelling of the neck along the 

 jugular furrows, and in the dikkop, or big-head variety, the head and neck 

 may be swollen to an enormous size, the eyes closed up, and the con- 

 junctiva protruding. These symptoms are followed by weariness. The 

 animal stands lazily, rests its head on the manger or against the wall, 

 resting one leg then the other, and in final .stages refuses food, although 

 in the beginning appetite is unimpaired; breathing increased to thirty 

 or over per minute, pulse small, quick, and hard, which soon becomes 

 feeble, often intermittent, and auscultation of the heart generally gives 

 tumultuous or palpitating sounds. There is a jugular pulse, animal lies 

 down and soon gets up again. About this stage a yellow clear fluid 

 discharges from both nostrils. On auscultation at the thorax, the breath- 

 ing is audible, and of a gurgling sound, which gives one the impression 

 there is a fluid in the bronchial tubes ; respiration is hurried and laborious, 

 the animal falls or lies down, and dies suddenly. Frequently, a few 

 minutes before death, a great quantity of white froth is blown from the 

 nostrils, and almost invariably at death this froth appears at the mouth 

 and nose, which retains its form, and does not become fluid till some 

 time after death. 



" This froth is the yellow fluid mixed with air from the lungs, and, 

 according to Edington, is blood serum. The commonly observed symptoms 



