COTTONSEED BY-PRODUCTS 



119 



with symptoms of diarrhea, bloody urine, gastroenteric catarrh, often 

 of a hemorrhagic nature, nephritis, abortion, etc. Postmortem examina- 

 tions usually reveal hemorrhages in the mesentery, intestines and kid- 

 neys, ascites, cloudy swelling of the heart, liver and kidneys and cardiac 

 paralysis. 



The harmful principle in cottonseed has not been definitely determined 



Fig. 52. Cocoanut palm. 



Fig. 53. Cocoa nut. a, Outer fruit covering; 

 b, fibrous envelope; c, inner fruit shell; d. seed 

 shell; e, endosperm of the seed proper; f, cavity, 

 filled with "milk" when fresh. 



but in all probability this is of the nature of bacterial products (p. 147). 

 Prolonged heating destroys the toxic substance. 



Cornevin succeeded in extracting the toxic principle with water and 

 killing dogs with subcutaneous injections. Symptoms, diarrhea and loss 

 of consciousness. Withers and Carruth extracted gossypol with ether 

 after the seeds had been decorticated and the fat removed with gasoline. 

 Gossypol killed guinea-pigs when injected intraperitoneally. Since young 

 stock and pigs are more sensitive to the effects of the toxic principle 

 in cottonseed, the latter is usually withheld from them. Furthermore, 

 these products are unsuited for pregnant animals and those that are 

 suckling their young. 



