CONTENTS 



CHAPTER. PAGE 



PREFACE vii 



LIST OF ILLUSTRATIONS xi 



INTRODUCTION xiii 



I. VIRULENCE OF ORGANISMS i 



II. GENERAL CONDITIONS OF INFECTION AND RESISTANCE n 



III. THE GENERAL PHENOMENA OF IMMUNITY 16 



TYPES OF IMMUNITY. 



THEORIES OF IMMUNITY. 



SITE OF ANTIBODY FORMATION. 



IV. TOXINS AND ANTITOXINS 37 



BACTERIAL TOXINS AND ANTITOXINS. 



DIPHTHERIA. 



TETANUS. 



DYSENTERY. 



BACILLUS BOTULINUS. 



GAS BACILLUS. 



BACTERIAL HEMOTOXINS 

 PHYTOTOXINS. 

 ZOOTOXINS. 



V. AGGLUTININS AND PRECIPITINS 78 



BACTERIAL AGGLUTININS. 



HEMAGGLUTININS. 



PRECIPITINS. 



VI. CYTOLYSINS 115 



HEMOLYSINS. 

 CYTOTOXINS. 

 BACTERIOLYSINS. 



VII. CELLULAR RESISTANCE 151 



PHAGOCYTOSIS. 



OPSONINS. 

 OTHER FORMS OF CELLULAR RESISTANCE. 



VIII. COMPLEMENT FIXATION 173 



THE BORDET-GENGOU PHENOMENON. 



IX. APPLICATION OF COMPLEMENT FIXATION TO THE DIAGNOSIS OF DISEASE. 186 

 THE WASSERMANN REACTION. 

 COMPLEMENT FIXATION IN TUBERCULOSIS. 

 COMPLEMENT FIXATION IN GONOCOCCUS INFECTIONS. 

 OTHER COMPLEMENT FIXATION TESTS. 



X. HYPERSUSCEPTIBILITY 208 



ANAPHYLAXIS. 



ANAPHYLACTOID PHENOMENA. 

 RELATION OF ANAPHYLAXIS TO IMMUNITY. 



XI. HYPERSUSCEPTIBILITY IN MAN 228 



SERUM DISEASE. 

 ANAPHYLACTIC SHOCK. 

 NATURAL HYPERSUSCEPTIBILITY. 

 THE TUBERCULIN AND SIMILAR TESTS. 



XII. DEFENSIVE FERMENTS 245 



THE ABDERHALDEN TEST. 



APPENDIX. 



A. THERAPEUTIC EMPLOYMENT OF BLOOD SERUM 252 



B. PROPHYLACTIC VACCINATION .' 272 



C. VACCINE THERAPY 296 



