APPENDIX C 

 VACCINE THERAPY 



INTRODUCTION. 



DISEASES OF THE GENITO-URINARY TRACT. 



GONORRHEA. 



CYSTITIS. 



PYELITIS AND SUPPURATIVE NEPHRITIS. 

 DISEASES OF THE SKIN. 



FURUNCULOSIS. 



CARBUNCLES. 



ECZEMA. 



RINGWORM. 



OTHER SKIN DISEASES. 

 DISEASES OF THE RESPIRATORY TRACT. 



RHINITIS. 



OZENA. 



ASTHMA. 



PERTUSSIS. 



PNEUMONIA. 



OTHER DISEASES. 

 DISEASES OF THE EYE. 

 DISEASES OF THE ALIMENTARY CANAL. 



TYPHOID FEVER. 



PARATYPHOID FEVER. 



DYSENTERY. 

 TUBERCULOSIS. 



VACCINE THERAPY 



Introduction. A clear differentiation must be made between 

 prophylactic vaccination and therapeutic vaccination. The value of 

 various modes of prophylactic vaccination has been discussed and their 

 importance in protection against various diseases has been outlined. 

 For purposes of discussion of therapeutic vaccination it is well to con- 

 sider the infectious diseases as either acute or chronic and either local 

 or general. Acute infectious processes are for the most part self- 

 limited and require little in the way of specific treatment, and spon- 

 taneous cure is so regular as to render difficult the interpretation of 

 results following therapeutic vaccination. Chronic infectious diseases 

 tend to be progressive and finally result either directly or indirectly in 

 the death of the patient. Statistical reports may show instances of 

 amelioration of the disease, but the personal bias of the investigator 

 may sometimes confuse the conclusion. Generalized infections may be 

 treated by simple bacterial vaccination, but the results with sensitized 

 vaccines have been better than those with unsensitized vaccines. With 

 few exceptions the results of therapeutic vaccination have been best 

 in cases of localized infection. The vaccines employed may be in the 

 form of stock vaccines, but the opinion is practically universal that 

 wherever possible the employment of autogenous vaccines gives the 

 best results. 



The persistence of chronic infections is, in part, due to the fact that 

 the chronic inflammatory fibrous tissue hinders the general absorption 

 of antigenic materials produced by the exciting organism. Conse- 

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