ELEMENTARY GRANULES. 11 



be directly observed. A matrix lastly, is found in cartilages 

 and bones as a solid, homogeneous, granular, or even fibrous 

 substance connecting the cellular elements and for the most 

 part arising from the blood, independently of them. 



[The occurrence of a solid blastema, growing independently, 

 in the villi of the chorion and of a solid matrix deposited 

 directly out of the blood, demonstrates that all parts of the 

 body are not, as Schwann was disposed to believe, without ex- 

 ception developed from cells or in dependence upon cells. A 

 few more recent authors, as lleichert, Donders, and Virchow, 

 also consider that the connective tissue, excepting its elastic 

 element, is to be reckoned among those tissues which are not 

 at all, or not wholly, derived from cells ; but, as we shall see 

 below, incorrectly. On the other hand, it is certain that in 

 pathological formations such masses very frequently occur, 

 fibrinous exudations becoming changed in great measure, with- 

 out previous organisation, i. e. cell formation, into permanent 

 tissues.] l 



A. SIMPLE ELEMENTARY PARTS. 



I.— ELEMENTARY GRANULES, ELEMENTARY VESICLES, NUCLEI. 



§ 6. 

 In almost all animal fluids, whether contained in canals, or 

 inclosed in cells, as well as in many more solid tissues, there 

 are found and often in immense quantities, roundish corpuscles 

 of very small, hardly measurable dimensions. Henle has called 

 them elementary granules, and has expressed the opinion that 

 they are vesicular. This, however, is not always true, since it 

 is demonstrable that many of these corpuscles possess no in- 

 vestment. Such is the case with the fatty particles which occur 

 in many cells and glandular secretions, with the granules of 



[' The Enamel and the Dentine of the teeth, and the so-called Cuticle of the 

 hair, (see §§ on Hair and Teeth, and 'Quarterly Journal of Microscopical Science' 

 for April, 1853,) must certainly be regarded as structures which are not derived 

 directly from the metamorphosis of cells. We are inclined also to believe, that the 

 opinion of Reichert, Donders and Virchow, as to the nature of the connective tissue, 

 deserves much more attention than Professor KSlliker seems disposed to bestow on it. 

 See §§ on Connective and Elastic Tissues, ami General Appendix. — Ed 



