OF THE GLANDS OF THE SKIN. 213 



minal coil : like the hitter it was composed of the original 

 though thickened membrane continuous with the surface 

 of the corium, and of an epithelium consisting of many- 

 layers of pale, polygonal, or rounded cells. The glands of the 

 rest of the body, about this period, appeared to me to be simi- 

 larly constituted. I can say nothing as to their earlier condition, 

 but even those of the axilla were in no wise distinguished from 

 the rest. From this time the development goes on very rapidly; 

 the end of the gland elongates more and more, and coils itself 

 up (fig. 82 B), so that it assumes an appearance hardly 

 different from that which it presents in the adult. In the new- 

 born infant, the glandular coils in the heel measure 006 — 007'" 

 (in a child of four months 0'06 — O'l'" on the heel, in the hand 

 0-12"'), present much convoluted canals of 0015 — 0"02'", and 

 traverse the epidermis with their already twisted ducts (in the 

 corium of 0008'", in the rete Malpighii of 0-022"') . 



It results from these facts that the sudoriparous glands are 

 nothing else than involutions of the skin, and do not begin as 

 hollow structures, but are at first a simple development of the 

 stratum mucosum. By a continual process of cell-multiplication, 

 the original rudiments grow deeper and deeper into the skin, 

 acquire their peculiar spiral windings, and divide into the 

 glandular coil and the sweat-duct ; while at the same time, 

 either by liquefaction of their central part, which would thus, as 

 it were, represent a first secretion, or by the excretion of a fluid 

 between their cells, a cavity is produced. How the sweat-duct 

 in the epidermis and the pore are formed is doubtful; pro- 

 bably by a formative process in the epidermis itself. According 

 to a few measurements which I have instituted (' Mikroscop. 

 Anat./ II, i, 171), a development of sudoriparous glands 

 appears to take place even after the fifth month, whilst the 

 whole number appears to exist at birth. 



[Little is known as to the pathological conditions of the 

 sweat-glands. Kohlrausch (Muller's 'Archiv/ 1813, p. 366), 

 has found them of considerable size (£'") in an ovarian cyst, 

 together with hairs and sebaceous follicles. In Elephantiasis 

 graecorum, G. Simon and Briicke (Simon, ' Hautkrank.,' 

 p. 268), noticed an increase in size of the sudoriparous glands, 

 and V. Barensprung observed the same thing in a kind of 



