ALBUMOSES AND AMINOACIDS 57 



Resorption of Iodized Proteins. The author, in associ- 

 ation with M. Friedmann, has attempted to solve this 

 difficulty by a study of the resorption of iodized proteid 

 substances. 26 Isolation of no particular metabolic product 

 containing iodine was sought, but rather the iodine dis- 

 tribution. One can in this way determine after admin- 

 istration of an iodized protein what part of the iodine 

 present at a given time in the intestinal content, the intes- 

 tinal wall, in the blood and urine, exists in the form of in- 

 coagulable organic substances which can be precipitated by 

 phosphotungstic acid (albumoses and peptones), in the form 

 of incoagulable organic substances not precipitated by phos- 

 photungstic acid (aminoacids), and finally how much exists 

 in inorganic combination. The results obtained indicate 

 that at least the bulk of the determined iodo-proteid sub- 

 stance (iodo-proteic acid) in absorption from the intestine of 

 a cat is so completely dissociated that the iodine in the 

 intestinal wall and blood appears, not in form of iodized 

 albumoses or peptones, but as inorganic alkali iodides. 



Objections to the Resorption of Albumoses and Amino- 

 acids. Otto Loewi 27 has pointed out that as a matter of fact 

 the toxicity of albumoses and peptones introduced directly 

 into the blood circulation (referring to the reduction of blood 

 coagulability and the lowering of vascular tone in the 

 splanchnic area, shown by the investigations of Schmidt- 

 Muhlheim, Fano and others) is contradictory to the idea 

 that albumin is taken up in the form of peptone. To the 

 objection that any important formation of aminoacids in the 

 intestine would represent a waste of chemical tension energy 

 lost to no purpose in the splitting process, Loewi has shown 

 from Buhner's calorimetric determinations that in such a 

 process certainly not above 10 per cent, of energy is lost, 



28 O. v. Fiirth and M. Friedmann (Vienna), Arch. f. exper. Pathol. 

 ( Schmiedeberg's Festschrift), p. 214, 1908. 



27 O. Loewi (H. H. Meyer's Labor., Marburg), Arch. f. exper. Pathol., 

 48, 327, 1902. 



