218 CARBOHYDRATE-SPLITTING FERMENTS 



prove beyond doubt that the pancreas cannot possibly be the 

 only source of the blood diastase. They show that the curve 

 of the blood diastase, which is deeply depressed after pan- 

 creatic extirpation, rises again after a few days, without, 

 however, fully regaining its normal level. 80 It is not im- 

 probable that the liver may also give off diastasic ferment 

 into the blood, 81 more plausible in fact than the reverse 

 hypothesis that the hepatic ferment should be derived from 

 the blood. 



Maltases, Invertases and Gluceses in the Blood-serum. 

 Besides diastase maltase also is met in the blood serum. 

 This has been recently investigated closely in F. Rohmann's 

 laboratory. In connection with these studies brief inquiry 

 was made as to whether the maltase of the blood serum is 

 capable in concentrated solutions (as proved by Croft-Hill 

 for yeast maltase) of building disaccharides and poly- 

 saccharides from glucose molecules; points were noted 

 fundamentally corroborative of the conception of such 

 synthetic fermentation. Following a terminology proposed 

 by Euler we would here have to recognize the existence of 

 a "glucese" in the blood serum. 82 



There is, too, much of interest in the recognition by 

 Abderhalden that in the blood serum after parenteral intro- 

 duction of a group of carbohydrates which do not normally 

 enter the circulation (as cane sugar, milk sugar or starch) 

 ferments may be found which are capable of inducing cleav- 

 age of such substances. 83 



80 H. Otten and T. C. Galloway ( Carlson's Lab., Chicago ) , Amer. Jour, of 

 Physiol., 26, 347, 1910; cf. also S. van de Erve (Carlson's Lab.), ibid., 29, 182, 

 1911. 



81 A. Pugliese, Arch, di Farmacol., 12, 1, cited in Centralbl. f . Physiol., 20, 

 827, 1906. 



82 Cl. Kusumoto, L. Doxiades ( F. Rohmann's Lab. ) , Biochem. Zeitschr., 

 14, 217, 1908; 32, 410, 1911; 38, 306, 1912. 



83 E. Abderhalden, with C. Brahm, G. Kapfberger and E. Rathsmann, 

 Zeitschr. f. physiol. Chem., 64, 429, 1910; 69, 23, 1910; 71, 367, 1911. Litera- 

 ture upon Animal Invertases: C. Oppenheimer, Die Fermente, 3d ed., II, p. 40, 

 1910. 



