316 HYPOPHYSIS IN CARBOHYDRATE METABOLISM 



Consistently with the failure of adrenin glycosuria in 

 animals deprived of their hypophyses, in hypophyseal 

 obesity (degeneratio adiposo-genitalis), which is believed 

 to be connected with a lowered function of the hypophysis, a 

 higher tolerance for carbohydrates has been observed, as 

 in myxcedema. 47 As previously stated, the hypophysis may 

 be regarded as associated with the thyroid and the chrom- 

 affine system in a group of organs with sympathetic innerva- 

 tion, having an accelerator influence upon metabolism, and 

 under proper circumstances increasing the respiratory 

 metabolism as well as the carbohydrate-, protein- and fat- 

 exchange. Aschner 48 expresses this relation by the follow- 

 ing modification of the previously presented Eppinger-Falta 

 schema (including the ovary and the parathyroids) : 



THYROID 

 HYPOPHYSIS 



PANCREAS 



PARATHYROIDS 



OVARY 



Inhibition 



CHROMAFFINE 

 SYSTEM 



Without any desire to place any excessive provisional 

 estimate upon the reality of all these matters, it will be well 

 for us to follow with proper interest the further development 

 of this modern scientific magic, in which internal secretory 

 organs replace the planetary orbits of the ancient astrol- 

 ogers, with their favoring and inhibitory influences upon 

 every phase of life. 



With this, these little known subjects may be dismissed, 

 and with them that of glycosuria, attention being directed 

 to other matters connected with carbohydrate metabolism ; 

 of which the first to demand our interest are the glycuronic 

 acids. 



47 Cf. C. v. Noorden, Die Zuckerkrankheit, 5th ed., 1910, p. 48. 



48 Aschner, 1. c., p. 110. 



