334 SUGAR DESTRUCTION IN THE ECONOMY 



No great importance can be attributed by the author to 

 experiments with tissue pulp, 16 as the technical difficulties of 

 antiseptics with such material seem at the present, at least, 

 not overcome. The author, however, acknowledges an im- 

 pression that it may be a mistake to set aside without further 

 consideration as "the effects of bacteria" the results of all 

 experiments upon the glycolytic action of expressed juices 

 provided they are conducted with necessary antiseptic pre- 

 cautions. 



Possible Existence of Glycolytic Tissue Ferments. One 

 should remember, for instance, that, according to Fein- 

 schmidt, 17 in the expressed juices from the pancreas, liver 

 and muscles, even in the presence of 0.9 per cent, of sodium 

 fluoride, appreciable glycolysis, with development of CO 2 

 and organic acids, but with only traces of alcohol, is said to 

 take place. It is without doubt of importance, too, that 

 Cohnheim's work should have been confirmed by the Amer- 

 ican, Hall, 18 in a very carefully conducted and critical con- 

 trol experiment. Hall expressed the juice from muscle and 

 pancreas; and with these and with alcoholic extracts (by 

 boiling) from the latter, mixed or separate, acted upon a 

 dilute sugar solution at incubator temperature and in pres- 

 ence of toluol, the length of the experiment not exceeding 

 three days. That he should have found as an average from 

 his experiments that pancreatic juice alone destroyed only 

 0.3 per cent, of the amount of glucose employed, muscle juice 

 alone only 1.6 per cent., the combination of muscle juice and 

 pancreas 4.4 per cent., but the combination of the alcoholic 

 extract of pancreas and muscle-juice as much as 18.3 per 

 cent., is very remarkable. The objection that such results 

 are entirely due to bacterial influences seems decidedly im- 



16 Literature : ( Blumenthal, Ssobolew, Herzog, Feinschmidt, Arnheim and 

 Rosenbaum, Sehrt, Rapoport, Braunstein, Simacek, R. Hirsch) in Rosenberg, 

 Handb. d. Biochem., 3', 253, 1910. 



17 Feinschmidt, Hofmeister's Beitr., 4, 511, 1904. 



U C. W. Hall (Harvard Medical School), Amer. Jour, of Physiol., 18, 

 283, 1907. 



