354 DIGESTION AND RESORPTION OF FATS 



are changed into triglycerides. The fatty acids essential 

 for this synthesis requisite to completely transform the 

 monoglyceride into triglyceride must first, however, be ob- 

 tained from cleavage of the former. The inference that any 

 extensive cleavage of ingested fat must occur is not to be 

 made, however, from this point. 



Behavior of Nonr-saponifiable Emulsions. The clearest 

 indication that the intestine does not take up the fat ex- 

 clusively in the form of an emulsion, but at least partly in 

 a dissolved state, may be seen, to the author's mind, in 

 the fact that even the finest emulsion of lanolin, 12 petroleum 

 or paraffin (material which from its chemical peculiarities 

 cannot be converted into a dissolved form in the intestine) 

 is not open to absorption. If neutral fat be incorporated 

 with soft paraffin by melting them together and the mixture 

 introduced into the intestine in finely emulsified form, the 

 bowel wall takes up only the fat, but rejects the paraffin. 13 

 The writer is disposed to regard this as a thoroughly 

 crucial experiment. The statement of Hofbauer and S. 

 Exner, 14 subsequently confirmed by Lafayette Mendel, 

 that fat colored with suitable staining reagents can pass 

 into the chyle ducts as stained fat has no further reference 

 to the method of resorption in the opinion of Pfliiger, and, 

 too, of L. B. Mendel, than to indicate that these staining 

 substances are soluble in free fatty acids or in a biliary 

 solution of fatty acids and soaps, the latter being quite 

 capable of acting as a vehicle to aid the passage of the stain- 

 ing substances through the wall of the intestine into the 

 chyle ducts. 15 



13 W. Connstein, Arch. f. Anat. u. Physiol., 1899, 30; A. v. Fekete (Physiol. 

 Instit., Budapesth), Pfliiger's Arch., 139, 211, 1911. 



13 V. Henriques and C. Hansen, Centralbl. f. Physiol., 14, 313, 1900. 



14 L. Hofbauer (S. Exner's Lab., Vienna), Pfliiger's Arch., 81, 263, 1900; 

 84, 619, 1901; Zeitschr. f. klin. Med., 47, 475, 1902; S. Exner, Pfliiger's Arch., 

 84, 628, 1901 ; L. B. Mendel (Yale Univ.) , Amer. Jour, of Physiol., 24, 493, 1909. 



15 E. Pfliiger, Pfliiger's Arch., 81, 375, 1900; 85, 1, 1901; L. B. Mendel, 

 1. c.; cf. also L. B. Mendel and A. L. Daniels (Yale Univ.), Jour, of Biol. 

 Chem., IS, 71, 1912. 



