PARENTERAL FEEDING WITH SUGAR 511 



ministration of protein. From studies in this connection by 

 Stolte, Salaskin and Kowalewski, Abderhalden and his asso- 

 ciates, and from those of Wohlgemuth, but particularly from 

 very recent investigations in Bottazzi's laboratory, 81 the 

 results clearly indicate that aminoacids injected into the 

 blood are eliminated only in a small fraction by way of the 

 kidneys, that the bulk disappear within the body, and that 

 there is no intrinsic reason why we should not attribute to 

 them the possibility of taking part in the up-building of 

 protein in the system. It seems, too, that aminoacids can be 

 introduced directly in the veins of an animal in quantities 

 quite sufficient for the nitrogen requirements of the animal 

 without the necessity of fearing severe toxic phenomena. 

 Our experience with the matter is, however, as yet not 

 extensive enough to justify a final opinion. 



The ability of the body to handle parenterally introduced 

 proteins is explicable from the investigations of Abderhalden 

 and his collaborators, who have shown by the " optical 

 method " that the plasma of animals, after parenteral injec- 

 tion of proteins and high molecular products of protein- 

 cleavage, possesses the power to catabolize these substances. 

 It seems that under these circumstances the formed elements 

 of the blood and other body cells give off peptolytic ferments, 

 just as, according to Abderhalden and to Heilner, after 

 parenteral introduction of compound carbohydrates (as 

 cane-sugar, milk-sugar and starch) ferments appear de novo 

 in the plasma which induce cleavage of these substances. 82 



Parenteral Feeding with Sugar. What may be accom- 

 plished in the way of parenteral nutrition with sugar ? 



In this connection attention may be called to a series of 

 very interesting observations recently collated by W. 



81 G. Buglia (F. Bottazzi's Lab., Naples), Zeitschr. f. Biol., 58, 162, 1912, 

 and earlier studies; cf. therein Literature. 



82 Abderhalden's works on the proof of proteolytic and peptoly/tic ferments 

 after introduction of specifically foreign and blood-foreign proteins and peptones 

 are collected in Abderhalden's Synthesis der Zellbausteine < Berlin, J. Springer, 

 1912), pp. 119-120. 



