1863.] 495 



in appearance and properties from the acid oxalate, C 40 H 24 N 2 O 4 , 

 H 2 C 4 O 8 + 2Aq, obtained by Van Heijningen. 



Pier ate of Quinidine. Quinidine dissolves in a boiling and not 

 too concentrated solution of picric acid ; but it separates on cooling, 

 not in crystals, but as a resinous mass. Wben dissolved in hot 

 alcohol, it is deposited by evaporation of the solution in resinous 

 nodules, thus very closely resembling the corresponding salt of 

 quinine. 



Action of Iodide of Ethyl on Quinidine. Iodide of ethyl attacks 

 quinidine very readily, so that if the two substances (the former 

 being in excess) be heated together in a flask furnished with a per- 

 forated cork and long tube to condense the iodide of ethyl, com- 

 bination quickly ensues, and in half an hour the reaction is complete. 

 Water is then added and the excess of iodide distilled off, the residue 

 dissolved in dilute alcohol, filtered, and allowed to crystallize. On 

 cooling, the solution becomes semisolid, from separation of the 

 iodide of ethyl- quinidine in the form of long silky needles. These 

 are well washed with cold water, in which they are almost insoluble, 

 and then recrystallized from boiling dilute spirit, washed, dried at 

 100, and submitted to analysis. 



5600 gramme yielded '2735 gramme iodide of silver, equivalent 

 to -1478 of iodide, or 26-39 per cent. 



The formula C 4oH 24 ^N 2 O 4 j j re q U i reg 25.45 per cent, of iodine. 



Platinum-salt of Ethyl-quinidine } 



On treating the foregoing iodide with chloride of silver the chlo- 

 rine replaces the iodine, and we obtain chloride of ethyl-quinidine in 

 solution and iodide of silver. The latter is separated by filtration, 

 and the solution, now free from iodine, is precipitated by the addition 

 of bichloride of platinum. The platinum- salt separates as a pale- 

 yellow powder, almost insoluble either in hot or in cold water, and 

 but sparingly soluble in boiling dilute hydrochloric acid, from which 

 it separates almost completely on cooling. 



The specimen analysed was simply washed with water and dried 

 at 100. *537 gramme gave *137 metallic platinum, corresponding 

 to 25' 61 per cent. 



2N2 



