496 [March 19, 



The formula C 40 H 24 N a O^^jp 1 2 Pt C1 3 requires 25-86 per 

 cent. 



Hydrated Oxide of Ethyl-quinidine. On treating the iodide of 

 ethyl- quinidine with oxide of silver in slight excess, a solution of the 

 hydrated oxide is obtained. It is very bitter to the taste, readily 

 attracting carbonic acid from the air, and is of course highly alkaline 

 to test-paper. On evaporation it does not crystallize. 



Action of Iodide of Ethyl on Hydrated Oxide of Ethyl-quinidine. 

 When iodide of ethyl and a strong solution of hydrated oxide of 

 ethyl-quinidine are made to react upon each other in a sealed tube 

 at the temperature of 100, a mass of crystals are produced after 

 digestion for about an hour. These were extracted from the tube, 

 washed with a little water, dried between folds of filtering-paper, and 

 recrystallized from dilute alcohol. On analysis, they proved to be 

 nothing more than reproduced iodide of ethyl-quinidine. 



4435 gramme gives '2165 of iodide of silver, corresponding to 

 117 of iodine, or 26*38 per cent. 



The formula C 4o H 2i N 2 O 4 | j re( j u ; reg 25.45 per cent. 



From these experiments it appears that quinidine contains no 

 replaceable hydrogen, and in this respect it agrees with quinine and 

 cinchonine, the alkaloids with which it is associated. 



Double Tartrate of Quinidine and Antimony , 



C 40 H 24 N a 4 H 1 c H 

 SbOJ U 8 U 4 U i3' 



When an excess of quinidine in powder is added to a cold saturated 

 solution of tartar-emetic, and heat applied so soon as the mixture 

 begins to boil, the quinidine pretty rapidly dissolves, whilst at the 

 same time a quantity of oxide of antimony is precipitated. The 

 solution is filtered whilst boiling, and on cooling the double tartrate 

 of quinidine and antimony is deposited in very long fine silky needles, 

 often more than an inch in length. Any excess of quinidine which 

 has been employed, together with the oxide of antimony which has 

 been precipitated, remains upon the filter. The double tartrate is 

 but slightly soluble in cold water, but dissolves easily in hot, from 

 which it may readily be crystallized. It is also very soluble in 

 boiling spirit of wine, from which it is deposited, almost completely 

 on cooling, in tufts of slender needles. 



