in MI.AXS or \IALYSTS riM-:n;n i<>\. 



Sxnlhelic camphor. i| h . weak dexl r.:i ml ;il ion ,,f which vvils 

 cmnpeii-atr.l with Hie aeee \ATj aiiimiiil nf I camplmr. wa 



used i" prepare ;i bromcamphowarboxylic '""/ which was 



rom/y/r/r/// uuirlin-. ThU acid wa- n^-d I'm- tin- t'nl lowing 

 act ivaliiiM experiments. 



1. \Villi <inininr. Since with tin- alkaloid ||,,. | ;i,-i(l 

 decompose! in ire rapi-lly limn ihr .1 ftcid, OHe -li"iil.| 

 lliiil. (In- tmdeOOXnpOeed :i-il u the ..nc li;m I \vdiihl he 

 rotatary, :MI.| OB lln i >llu-r the lii-nin,-;iiii|.li..i-. whi.-h is foniinl 

 liv (lie read i'ii. \\"ii| ( | !< .|c\lrn rii:ihir_\ . 



lln- deOOmp08iti<Hl OUnre il L r-'iiii.l lluil tin- IIK.S- 

 in^mcnl I'm- >ln||.in;.- the reach ii i- iii tin- mil .f 



IS miiiiitrs. T\VM |,;u-;il|(.| (-XJ)cri UU'll t S \\<T<- !n;n|.-. ... 1)000 



gram >f Inactive bromoamphor-oarbo^ic ;i-i.l were 



ill '<> mil. nf iircln|i||i'||nin> ;ni,| m i\<-| \\ilh ., ,-,-|il. ,!' 



i>h<'ii"nr \\hich c.,ni;iinc.| (). 1000 n TJ , m ,,i' quinine. 'l'h- mixture 



was place,! in a .ihcrniM iai a,,,| krpl at |o fa 88 iniinit.rs, nt 

 'lu- end "I" \\hidi time il Wat mixed \\ilh 10 OOm, "I" a dilute 



-"luii'Mi <d' livdruchlni-ic acid and l.uricd in ; , freezing mixture 



Of :ill and icc. The h vdrnclilm-ic a<-id u'as previously sat.nriiled 



\\iih cnninmn salt HO as in eauee the layer of the acid wlution 

 111 eparate i'r the aoetophenone eoluption tno^e oui<jkly, The 



'!' the |.\dn.c|il..ric acid snllltion se|'\ed the donl.le 

 Of -toppino- || M - react inn and remOTing I he .pnntiie 

 'I In- nptical rntalinu nf I he hyd mdilnr ic a.'M olutiOQ, af-li-r 



eparation from the aci-inphenmie layer, crai meji-un-d is- a 

 l <!cm. tnhe a. 1. 1 fniind to be: -li:i. Tin- aoteophenoae 



.'ollltinn \\a hakeii up l\Mr,. ;u ..,,,, with |O .-em. nf the 



hydrochloric acid. The < cond H ( 'I extract '\li-n p..]an ed 

 in M i donu tube wa< fmind in give ; rotation of vhih? 



the third extract ;-.i\c a rotation of; O .OO. O. |OOO u,-ain of 

 wa-, di^.^olveil in |O ccm. .!' the a!>.\< ||('| snluiinn 



wu toed for extracting the quinine from the 

 reaction mixture; ihi when p.,lan-.-d in a I d<-m. 



liihe and wa- fniiml tn oj\e a mi:iii >f - I .'.M;. thn 



-Imuii,.. thin one h.-ikin- with 10 com, d' the Ih'i olution 



