64 On the Passage of Substances into the Animal Tissues. [Feb. 9, 



lithium ; it was also killed, and when the whole lens was hurnt at once, no 

 trace of lithium could be found. In the other, which had taken lithium, a 

 piece of the lens, -g^th of a pin's head in size, showed the lithium ; it had 

 penetrated to the centre of the lens. 



In another pig the same quantity of chloride of lithium was given, and 

 in four hours even the centre of the lens contained lithium. 



Another pig was given the same quantity, and it was killed in two hours 

 and a quarter. The cartilage of the hip showed lithium faintly, but dis- 

 tinctly. The outer portions of the lens showed it slightly ; the inner portions 

 showed no trace. 



To a younger pig the same quantity was given, and it was killed in 

 thirty-two minutes. Lithium was found in the cartilage of the hip ; in the 

 aqueous humour ; distinctly in the outer part of the lens, and very faintly 

 in the inner part. 



In an older and larger pig, to which the same quantity was given, 

 lithium after one hour was found in the hip and knee joints very faintly ; 

 in the aqueous humour of the eye very distinctly ; but none was found in 

 the lens, not even when half was taken for one trial. 



Chloride of rubidium in a three-grain dose was not satisfactorily detected 

 anywhere. When 20 grains had been taken, the blood, liver, and kidney 

 showed this substance ; the lens when burnt all at once showed the smallest 

 possible trace ; the cartilages and aqueous humour showed none, probably 

 because the delicacy of the spectrum-analysis for rubidium is very much 

 less than that for lithium. 



A patient who was suffering from diseased heart took some lithia-water 

 containing 15 grains of citrate of lithia thirty-six hours before her death, 

 and the same quantity six hours before death. The crystalline lens, the 

 blood, and the cartilage of one joint were examined for lithium : in the 

 cartilage it was found very distinctly ; in the blood exceedingly faintly ; 

 and when the entire lens was taken, the faintest possible indications of 

 lithium were obtained. 



Another patient took lithia-water containing 10 grains of carbonate of 

 lithia five hours and a half before death : the lens showed very faint traces 

 of lithium when half the substance was taken for one examination ; the 

 cartilage showed lithium very distinctly. 



I expect to be able to find lithium in the lens after operation for cataract, 

 and in the umbilical cord after the birth of the foetus. 



I am, yours truly, 



H. BENCE JONES. 



February 9, 1865. 

 Major-General SABINE, President, in the Chair. 



Pursuant to notice given at the last Meeting, the Right Honourable 

 Lord Dufferin was proposed for election and immediate ballot. 



