1865.] of Cystic Entozoa in the Calf. 219 



appeared to have been absorbed, leaving only faint white spots to indicate 

 the situations where the cysts once were. Such, at least, is our interpre- 

 tation of the phenomena observed ; and, in this relation, we have only 

 further to remark that the heart-cysts were not merely found at the surface 

 of the organ, but were dispersed throughout its substance, one or two of 

 the better- formed vesicles being lodged within the septum ventriculorum. 



On the present occasion we do not propose to offer any lengthened 

 comment on the results of this experiment, but rather to let the facts 

 speak for themselves ; nevertheless, to impart an aspect of completeness to 

 our paper, we will offer one or two concluding remarks. 



So far as we are aware, only three experiments of this kind have been 

 previously performed on the calf namely, two by Leuckart, and one by 

 Hosier. In two of these instances the experimental animal perished, 

 whilst in the other case, as in our own, the creature barely escaped with 

 its life. To our animal we administered a larger number of proglottides 

 than had been given even in Mosler's case ; but, probably in consequence 

 of the embryonic immaturity of the contents of many of the eggs, we did 

 not get that fatal result which otherwise would inevitably have followed 

 from a larger migration of the cestode-progeny. We believe that by far 

 the greater proportion of the " measles" resulted from the second worm- 

 feeding, in which case they would have come from the hundred proglottides 

 not subjected to the action of alcohol. Although the characters presented 

 by the earlier-developed morbid symptoms, as well as the time of their 

 accession, induce us to attribute the diseased phenomena to the larvae set 

 free by the first "feeding," yet it is clear, from the feebleness of the 

 symptoms manifested, that only a very inconsiderable number of embryos 

 can have entered on their wanderings. In the second " feeding," how- 

 ever, the case is very different ; for here all the circumstances connected 

 with the subsequent and marked disturbance of the animal's health point 

 unequivocally to the development of that peculiar form of parasite-disease 

 which Leuckart has designated as the "acute cestode tuberculosis." 



From the number of young vesicles present in the minute portion of 

 muscle removed by operation from the living animal, we had (in the pages 

 of the ' Lancet ') publicly announced our belief that we might ultimately 

 find 30,000 Cysticerci developed in this calf; but as the larvae were subse- 

 quently found to be almost entirely confined to the superficial muscular 

 layers, it turned out that our calculation was considerably beyond the 

 mark. Nevertheless from post-mortem data we estimate that there were 

 between seven and eight thousand " measles " present, and one of us 

 counted 130 vesicles at the surface of a single muscle. 



Lastly, it only remains for us to express our thanks to those gentlemen 

 who supplied us with the necessary experimental material, namely, to Dr. 

 Greenhow for the first tapeworm employed, and to Dr. Anderson and Mr. 

 Brookhouse (Nottingham) for the second and third tapeworms, which were 

 given together at the second administration. Dr. Greenhow's specimen 



VOL. xiv. s 



