1865.] into and out of the Vascular and Non-vascular Textures. 403 



the lens, even in its most central part. There was scarcely any difference 

 between the inner and outer part. The vitreous and aqueous humours 

 showed much more evidence of lithium than the lens itself did. 



Experiment 8. A guinea-pig, the urine of which gave no trace of 

 lithium, had three grains of chloride of lithium, and was killed in two and 

 a half hours. The lithium was found in the cartilage of the hip-joint dis- 

 tinctly but faintly. The blood showed the lithium very distinctly, much 

 more so than in any of the previous experiments. The outer portion of the 

 lens showed lithium, though but slightly. The inner portions of the lens 

 showed more. The vitreous and aqueous humours showed lithium very 

 distinctly. 



Experiment 9. A large guinea-pig was given three grains of chlo- 

 ride of lithium, and it was killed in an hour. Lithium was found in 

 the blood, urine, and nails very distinctly ; in the cartilage of the hip- and 

 knee-joints very faintly ; in the vitreous and aqueous humours of the eye 

 very distinctly. No lithium was found in the lens, not even when half the 

 lens was taken for a single experiment. The stomach contained food. 



Experiment 10. Another guinea-pig was killed an hour after the same 

 dose. The lithium was found strongly in the blood, bile, liver, and kidney. 

 Traces occurred in the brain and in the cartilage of the hip-joint. It was 

 present distinctly in the humours of the eye and in the lens. The differ- 

 ence between the inner and outer part of the lens was very marked. The 

 second eye was not examined for more than fourteen hours after the first 

 eye. After this time the centre of the lens contained as much lithium as 

 the outer part did. The stomach contained water. 



Experiment 11. A young guinea-pig, fasting, was given three grains of 

 chloride of lithium, and thirty-two -minutes afterwards it was killed. Li- 

 thium showed faintly in the cartilage of the hip-joint ; very distinctly in 

 the humours of the eye ; distinctly in the outer part of the lens, very faintly 

 in the inner part ; nearly the whole of the inner part had to be burnt to 

 give the appearance. Lithium was very distinct in the blood, and re- 

 markably so in the nails. 



Experiment 12. Another young guinea-pig, fed in the same way, and 

 bought at the same place as the two former, was killed without taking 

 any lithia. No lithium was found anywhere. The whole of the spleen, 

 one kidney, and one lens were incinerated, and each ash was used for a 

 single experiment, and in no instance was lithium found. There was no 

 lithium in the cartilage of the hip-joint, nor in the blood, nor in the nails. 



Experiment 13. A very young and small guinea-pig that had been 

 kept fasting for thirty-six hours, was given three grains of chloride of 

 lithium, and it was killed in half an hour, the urine having been previously 

 examined, and no lithium found in it. Very much lithium was found in 

 the blood and in the urine ; very slight traces in the cartilage and in the 

 brain. The lens showed no lithium when incinerated entire, but the 

 aqueous extract of the lens showed minute traces of lithium. 



