1865.] into and out of the Vascular and Non-vascular Textures. 407 



lithium very distinctly. A small piece taken from the cartilage of the 

 hip-joint showed only traces of lithium. 



The fifth was killed in ninety-six hours. The lens showed no lithium 

 even when a considerable proportion of it was taken for one experiment. 

 The aqueous extract of half one lens showed no lithium. A small portion 

 of the cartilage of the hip-joint showed no lithium. The urine showed 

 lithium very distinctly even in one drop. 



Experiment 19. Six fresh guinea-pigs were taken. The first was killed 

 and examined, having had no lithium. The two lenses, incinerated and 

 treated with sulphuric acid and alcohol, showed no lithium. The ash of 

 the kidney showed no lithium directly, but when treated with sulphuric 

 acid and alcohol, showed a distinct trace of lithium. 



The five others were given each one grain of chloride of lithium. 



The first was killed five and a half hours after the dose. The cartilage 

 of the hip-joint showed lithium faintly when merely touched with a red- 

 hot wire. The lens showed lithium distinctly in the outer part, scarcely 

 a trace in the inner part. The vitreous and aqueous humours showed 

 lithium very distinctly. The stomach was quite full. 



The second was killed twenty-four and a half hours after the lithium 

 was taken. The cartilage of the hip-joint showed no lithium even in a 

 small particle scraped off the surface. The lens still showed lithium dis- 

 tinctly, though less so than in the first; no difference was perceptible 

 between the inner and the outer portion. 



The third was killed in forty-eight hours. The lens showed no lithium 

 in a small particle taken on a loop of the wire. The aqueous extract of 

 the lens showed only faint traces of lithium. The urine showed lithium 

 very distinctly in a single drop. 



The fourth was killed in seventy- two and a half hours. The lens 

 showed no lithium when the ash was treated with sulphuric acid and 

 alcohol. The ash of the kidney showed no lithium directly, but when 

 treated with sulphuric acid and alcohol, showed traces of lithium. The 

 urine still showed lithium distinctly in one drop. 



The fifth guinea-pig : on the seventh day after the dose, the urine showed 

 lithium in one drop ; ninth day, still faint traces of lithium in the urine ; 

 eleventh day, urine directly shows no lithium, but the ash still shows 

 faint traces ; thirteenth day, ash of urine shows no lithium, but alcoholic 

 extract shows lithium distinctly ; fourteenth day the same ; sixteenth day 

 the same ; thirty-sixth day, when killed, no lithium could be detected in 

 the bones, nerves, lens, or vitreous or aqueous humours, nor in the urine, 

 kidney, or liver. 



Experiment 20. Two guinea-pigs, in the urine of which no lithium 

 could be detected, were given each half a grain of chloride of lithium. 



In three hours and fifty minutes afterwards one was killed. The car- 

 tilage of the hip-joint showed no lithium when simply touched with a red- 



2H2 



