408 Dr. B. Jones on the Passage of Crystalloids [1865. 



hot wire. Scrapings from the surface of the cartilage showed faint traces 

 of lithium. The sciatic nerve, humours of the eye, and the brain showed 

 faint traces. The muscles of the thigh showed the lithium much more 

 distinctly than the sciatic nerve. The lens showed lithium very dis- 

 tinctly in the aqueous extract, but not otherwise. The blood and bile 

 were very rich in lithium. The stomach was moderately full of food. 



The other animal, which was given half a grain, was kept until the 

 lithium ceased to appear in the urine. 



Fourth day. Lithium distinctly in the urine. 



Tenth day. Urine showed exceedingly minute traces of lithium. 



Eleventh day. Still traces. 



Thirteenth day. Urine shows no lithium in the quantity adhering to 

 the wire. 



Fourteenth day. Still lithium in the alcoholic extract. 



Twenty-seventh day. Still traces of lithium. 



Thirtieth day. The animal was found dead. 



The ash of the urine found in the bladder (about a quarter of an ounce) 

 showed no lithium. The alcoholic extract of the ash showed lithium 

 faintly. The alcoholic extract of the ash of one kidney showed no 

 lithium. And the alcoholic extract of the two lenses showed no lithium. 



Experiment 21. Two guinea-pigs, the urine of which contained no li- 

 thium, were each given one quarter of a grain of chloride of lithium. 



One was killed in four hours and thirty-five minutes. Lithium was 

 found very faintly in the spleen, very distinctly in the blood, in the urine, 

 and in the bile. Faintly in the sciatic nerve and in the brain. Very 

 faintly in the scrapings of the cartilage. Pretty distinctly in the vitreous 

 and aqueous humours, but very faintly in the aqueous extract of the lens. 

 The stomach was moderately full. 



The other was kept until the lithium ceased to appear in the urine. 



Second day. Lithium very distinctly. 



Fourth day. Minute traces of lithium. 



Sixth day. A drop or two of urine shows no lithium, but on evaporating 

 and incinerating one-twelfth of an ounce, the ash shows lithium very dis- 

 tinctly. 



Seventh day. Lithium still distinct in the ash. 



Eighth day. Still in the ash. 



Tenth day. Ash of urine shows only the merest trace. 



Eleventh day. Ash of urine shows no lithium ; but when treated with 

 sulphuric acid and alcohol, lithium is still distinct. 



Thirteenth day. Still lithium in one quarter of an ounce. 



Fourteenth day. Alcoholic extract from one-eighth of an ounce shows no 

 lithium. 



Sixteenth day. The animal was killed. The fluids and organs were 

 incinerated, the ash treated with sulphuric acid, excess of acid driven off 



