414 Dr. B, Jones on the Passage of Crystalloids [1865. 



S.45. Noiie. 



9.47-|. None. 



9.50^. A trace. 



9.52. A trace. 



9.55. Good. 



9.57|. Doubtful. 



10. Doubtful. 



10.5. More distinct. 

 10.10. Doubtful. 

 10.15. Doubtful. 



March 19. At 8 A.M. two cups of black coffee without milk, nothing 

 else taken. 



Urine from 9.50 to 9.56 collected ; contained no iodine. One grain of 

 iodide of potassium dissolved in one ounce of water was then taken. 

 9'58. No iodine. 

 9.59. No iodine. 

 10. None. 



10.1. None. 



10.2. None. 



10.3. None. 

 10-4. None. 

 10-5. None. 



10.6. None. 



10.8. Trace of iodine. 



10.10. Very marked iodine. 



10.15. Very marked. 



So that one grain of iodide of potassium in one ounce of water was de- 

 tected in the urine in twelve minutes, and was very marked in fourteen 

 minutes. Iron was detected once in seven minutes and twice in ten minutes, 

 and it was very distinct in fifteen minutes. 



Professor Mulder also made many experiments on this patient, but I am 

 unable to find any account of his results. 



In the 'Medical Gazette' for 1845, pp. 363 & 410, Mr. Erichsen gives 

 some experiments he made on a boy of thirteen who had an open bladder. 

 He states that twenty grains of ferrocyanide of potassium were detected in 

 one minute in the urine. The stomach was fasting, and the salt was dis- 

 solved in three ounces of water. Forty grains taken three quarters of an 

 hour after a full meal were only detected after thirty-nine minutes. 



Forty grains in four ounces of water were twice detected in two minutes, 

 and no trace could be found after twenty-four hours ; once in two minutes 

 and a half ; once in six minutes and a half ; once in fourteen minutes ; 

 once in twenty-seven minutes ; and once in thirty-nine minutes. 



Twenty grains of ferrocyanide he once detected for twenty-eight hours. 



It follows from these experiments that ten grains of carbonate or chloride 

 of lithium, taken two and a half, three, or four hours after food by a man, 



