120 Messrs. T. L. Brunton and J. Fayrer on the [Jan. 22, 



3.38. Respiration ceased. Carmula inserted in the trachea, and arti- 

 ficial respiration commenced. 



3.40. Sciatic nerve exposed and irritated by a strong current, induced 

 twitchings in the limbs, but occasioned no reflex movement in any other 

 part of the body. 



3.45. The animal seems perfectly dead. The strongest current pro- 

 duces no effect either when applied to the cord or to the sciatics. 



The colour of the muscles seems changed when compared with those of 

 the other rabbit (Experiment LXIY.) which had no poison. They are 

 of a less vivid colour, and altogether have an altered appearance. 



In this experiment the respirations became quickened from 37 to 96 

 per minute after the injection of the poison, although the cerebral lobes 

 had been previously removed. The acceleration, therefore, could not be 

 due to emotion, or to the action of the poison on the cerebrum. A com- 

 parison with Experiment LXIV., in which the cerebral lobes were removed 

 without injecting any poison, shows that in the latter no acceleration 

 whatever occurred, and the respirations became gradually slower till they 

 ceased. 



Experiment LXIV. 



July 21, 1873. A rabbit was etherized, the calvaria removed, and the 

 cerebral lobes carefully excised. The bleeding was arrested by cotton- 

 wool steeped in perchloride of iron ; and by the actual cautery. 



1.18. The operation concluded. 



1.23. Respirations 32 per minute. Reflex movements well marked on 

 pinching feet or tail. 



1.33. Eespirations 16 per minute and much deeper ; and each one ended 

 with a jerk, as if of the diaphragm. 



1.35. Pore legs extended in a convulsive manner. Respiration ceased 

 almost entirely ; but at long intervals of about 15 and 20 seconds, an in- 

 spiration occurred. 



On pinching the feet the respiratory movements became more perfect, 

 though feeble. 



1.43. Heart beats rapidly but feebly. Respiration has ceased. Reflex 

 movements are still well marked. 



1.44. Cannula placed in the trachea, and artificial respiration begun. 

 Reflex movements continued for some minutes ; but then the heart ceased 

 to beat. 



3.55. Sciatics exposed and irritated by a Faradic current. No con- 

 tractions occurred in the limbs. The muscles contracted when irritated 

 directly. 



From these experiments it was evident that the accelerated respiration 

 was not of cerebral origin; and it was therefore probably due to sti- 

 mulation of the pulmonary branches of the pneumogastric by the poison. 

 If this were so, the acceleration would not appear if the vagi were 

 divided previously to the injection of the poison, as the stimulation of the 



