TINOSPORA CRISPA 23 



from T. crispa. It is official in the Pharmacopoeia and has 

 been introduced into Europe. T. cordifolia has given excellent 

 results in the mild forms of intermittent fever j in general de- 

 bility following long and severe cases of illness ; in chronic 

 rheumatism, and in the second stage of syphilis. As the two 

 species are so much alike we shall add the preparations and 

 dose of T. cordifolia which we have used on several occasions 

 with good results. 



Tincture of T. cordifolia. — Stems of the dried plant, 

 100 grams. Alcohol 21° (Cartier), 500 cc. Macerate seven 

 days in a closed vessel stirring from time to time. After 

 decanting add enough alcohol (21°) to bring the quantity up 

 to 500 cc, and filter. 



Dose. — 4-8 grams. 



Maceration. — Fresh stems cut in small pieces, 30 grams, 

 water 300 grams. Macerate for two hours and filter. 



Dose. — 30-90 cc. a day. 



Extract. — Dry makabuhay in small pieces 500 grams. 

 Water 2J liters. Macerate for twelve hours, filter the liquid 

 and express the macerated drug which is then macerated a sec- 

 ond time in 2J liters of water. Express again, unite the two 

 liquids and filter. Evaporate in a water-bath to the consistency 

 of a pill mass. 



Dose. — J-1J grams a day in fractional doses. 



Botanical Description. — A vine whose runners entwine 

 themselves among the tops of the highest trees, giving oif 

 many adventitious roots which seek the earth. The stem is cov- 

 ered with projecting tubercles. Leaves heart-shaped, pointed, 

 entire with five well-marked nerves. Flowers yellowish-green, 

 dioecious, growing in axillary racemes. The male flowers have 

 a corolla of six petals, the three smaller ones arranged alter- 

 nately. In the female flower the stamens are represented by 

 three glands situated at the base of the petals. Fruit, an ellip- 

 tical drupe. 



