100 



A Bacteria-killing Globulin, 

 FIG. 1. 



[May 22, 



three and ninety-nine hours respectively. The spleen of A contained 

 rather few bacilli, either isolated or arranged in chains, which were 

 never longer than are occasionally met with in control rabbits after 

 simple inoculation with anthrax. In the lymph gland near the seat 

 of inoculation, however, they were often found in much longer chains, 

 or arranged in thick clusters. Of these chains, individual joints 

 often were swollen up or refused to take the stain. The bacilli in 

 B exhibited precisely similar appearances, but the chains of bacilli 

 were somewhat longer, occasionally consisting of twenty-seven or 

 twenty-eight joiiits. 



In another series of experiments the rabbits were infected by intra- 

 venous injection of the blood of a rabbit dead of virulent anthrax and 

 diluted with normal salt solution. Before or after this treatment, 

 5 10 c.c. of cell globulin solution were injected, intravenously. After 

 infection in this way the control rabbit died in twelve to eighteen 

 hours. The rabbits treated with the globulin occasionally lived for a 

 few hours longer, more often died at about the same time as the 

 control. The chains of bacilli in the spleen sometimes exhibited a 



