Dr. Noel Paton. On Hepatic Glycogenesis. 313 



November 16, 1893. 



Sir JOHN EVANS, K.C.B., D.C.L., LL.D., Vice-President and 

 Treasurer, in the Chair. 



Professor Arthur Mason Worthington was admitted into the 

 Society. 



A List of the Presents received was laid on the table, and thanks 

 ordered for them. 



In pursuance of the Statutes, notice of the ensuing Anniversary 

 Meeting was given from the Chair. 



Professor A. H. Church, Sir J. Cockle, and Professor W. C. 

 Roberts-Austen were by ballot elected Auditors of the Treasurer's 

 accounts on the part of the Society. 



The following Papers were read : 



I. "On Hepatic Glycogenesis." By D. NOEL PATON, M.D., 

 Superintendent of the Research Laboratory of the Royal 

 College of Physicians of Edinburgh. Communicated by 

 Professor McKENDRiCK, F.R.S. Received July 24, 1893. 



(Abstract.) 



Glycogenesis is here used in its original sense as indicating the 

 whole process of sugar production in the liver. 



The origin of sugar in the liver has been so conclusively demonstrated 

 that it is not considered. 



The evidence in regard to the relationship of hepatic sugar to- 

 hepatic glycogen is discussed, and is considered as conclusively in 

 favour of Bernard's original view. 



On the source of glycogen, all subsequent work has but established 

 Bernard's conclusion : " L'acte vital, c'esfc la production du glycogene 

 au sein du tissu vivant." 



On the mode of conversion of glycogen to sugar, more recent work 

 has not tended to confirm Bernard's view, that " L'acte chimique c'est 

 la transformation du glycogene en sucre." The question of whether 

 this conversion is due to a zymin, as held by Bernard, or to the vital 

 action of the liver protoplasm, as suggested by recent writers, is, as 

 yet, undecided. 



The object of the present communication is to elucidate this point, 



