1893.] Changes in the Blood consequent upon Inflammations. 487 



Conclusion :- 



1. Sugar when taken alone is a muscle food. 500 grams (17J 



ounces) of sugar increased in my case the amount of muscular 

 work done on a fasting day from 61 to 76 per cent. 



2. The muscle energy-producing effect of sugar is so great that 



200 grams (7 ounces) added to a small meal increased the 

 total amount of work done from 6 to 30 per cent. 



3. That when sugar was added to a large meal it increased the total 



amount of work done from 8 to 16 per cent. 



4. That the work done during a period of eight hours can be in- 



creased from 22 to 36 per cent, by taking 250 grams (8f ounces) 

 of sugar. 



5. That when sugar is taken at 3.50 P.M. it not only obliterates the 



normal diurnal fall in the muscular power, which usually 

 occurs at 5.30 P.M., but even causes an actual increase in the 

 total amount of work done. 



VI. " Note on some Changes in the Blood of the general 

 Circulation consequent upon certain Inflammations of an 

 acute local character." By C. S. SnERRiNGTON, M.D., F.R.S. 

 Received December 11, 1893. 



(Abstract.) 



This note describes, and attempts to interpret, in a preliminary 

 manner certain anatomical alterations in the blood noted in experi- 

 ments on the acute local inflammation of various tissues. The con- 

 tents of the communication are as follows : 



I. (1) Description of the method employed for the induction of 

 the local inflammation. 



(2) Description of the methods followed in examining the com- 

 position of the blood. 



II. Summary of the alterations observed. The chief of these 

 alterations are (1) inspissation of the blood ; (2) reduction of the 

 number of hsemic leucocytes followed by increase of the number of 

 them, followed in s^me cases by a final decrease of their number to 

 below the original normal ; (3) disturbance of the mutual ratios 

 normal between the different kinds of haamic leucocytes. The 

 summary is illustrated by quotation of protocols from certain of the 

 experiments 



a. When the site of inflammation is in the limb. 



S. When the site of inflammation is primarily peritoneal. 



</. When the site of inflammation is primarily in a mucous surface. 



