consequent upon Inflammations of acute local diameter.. 18P> 



Number of hyaline leucocytes in mm. blood . . ,....,....,. 2,760 



,, coarsely granular leucocytes iu mm. blood 1,080 , 



11.45 A.M. Temperature and respiration as before.. 



Sp. gr. of blood and serum. as before.. 



Haemoglobin value estimated at 47. 



Number of cliromocytes in mm. blood ... ... 7,450,000 1 



leucocytes in mm. blood' 16,960 



hyaline leucocytes in mm. blood 2,700 



,, coarsely granular leucocytes in mm; blood. 1,110 



11.45 12 noon. Lesion established in right pleural cavity. 



1 P.M. Temperature, 36'4. Respiration, 40; 



Sp. gr. of blood from ear , 1'0545 



Haemoglobin value.. ... 45 



Sp. gr. of blood serum.. . . ....... . . . 1'029 



Number of chromocytes in mm. blood 7,100,000 



leucocytes in mm. blood 39,120 



hyaline leucocytes in mm. blood 2,600 



coarsely granular leucocytes in mm. blood'. 610 



2.30 P.M. Temperature, 37'2. Respiration, 32. 



Sp. gr. of blood from ear T0545 



Haemoglobin value 46^ 



Sp. gr. of blood serum T0285 



Number of chromocytes in mm. blood 7,600,000 



,, leucocytes in mm. blood 44,410 



hyaline leucocytes in mm. blood 2,415 



,, coarsely granular leucocytes in mm. blood 585 



6.30 P.M. Temperature, 39'2. Eespiration, 34. 



Sp. gr. of blood T0495 



Haemoglobin value 41 



Sp. gr. of blood serum T028 



Number of chromocytes in mm. blood 6,840,000 



leucocytes in mm. blood 48,560 



hyaline leucocytes in mm. blood 2,530 



coarsely granular leucocytes in mm. blood 138 



Autopsy made at 7 P.M. revealed no haemorrhage ; I suspected tho 

 fall in the specific gravity might be due to haemorrhage, and so per- 

 formed autopsy at once to see the seat of it. There was a not very 

 copious exudation into the pleural cavity; the pleural surface showed 

 patches of inflammatory cells, but among these not many coarsely 

 granular were found in my examination of them. 



It is noticeable that, although the apoplasmia of the blood was here 

 absent, there was, nevertheless, a great reduction in the number of 

 coarsely granular leucocytes, not merely relatively to the rest of the 

 leucocytes, but absolutely per unit volume of blood. 



In the experiments with the ligation of a piece of intestine and 

 mesentery, the apoplasmia developed later than in the other series. 

 Copeman and myself* have noticed that in the rabbit the operation 



* Loc. cit., and ' Journ. of Physiol.,' vol. 14, p. 52. 



2 



