consequent upon Inflammations of acute local Character. 187 



[. Heidenhain*) succeed in proving, a sign and result of the amoeboid 

 stivity of the cell. If the cell is allowed to quiet slowly down be- 

 fore it is killed, I have shownf that the nucleus then very usually re- 

 turns to spheroidal form. Of course the cell body becomes spheroidal 

 much sooner than the nucleus. In the slowly killed cell the nucleus 

 usually becomes excentric in situation as well as spherical in shape. 

 It is also especially liable to smear. In the counting solution the 

 nucleus of this cell does not tinge so readily as does that of the 

 lyaline leucocyte. Under certain circumstances, when kept for a 

 lumber of hours in vitro, the nucleus of this leucocyte frequently 

 >resents a curious appearance I have not found described. The 

 ippearance is shown in figs. 6 and 7 (Plate 1). A number of portions 

 the nucleus are set in a wreath-like manner around the approxi- 

 late centre of the cell. 1 have never observed this arrangement in 

 the nucleus of the coarsely granular or hyaline leucocyte. 



Cell body : finely granular. The granulation of the cell body has 

 jen called " neutrophil " by Ehrlich,^ Bieder, &c. In the cat, 

 ider the prolonged action of aqueous methyl blue solutions, some 

 granules, especially in the neighbourhood of the nucleus, take on a 

 )right rose tint, and ultimately a considerable amount of rose- 

 jloured substance in rounded masses, some of large size, appears in 

 the cell. But the cell is much altered when this happens, and a good 

 leal of plasmoschisis has gone on. With less departure from the 

 lormal a good deal at least of the granulation of this cell can by 

 )ushing eosin or rnbin be coloured by these acid dyes; Kanthack and 

 Lardy consider them, strictly speaking, oxyphil. 



This cell is amoeboid. I have previously pointed out|| that at low 

 [16 C.) temperatures, it appears to be more amoeboid than is 

 the coarsely granular leucocyte. If kept for an hour or so in 

 banging drop at 42 C. this cell shows well the " excroissances sar- 

 tiques " of Dujardin, that, as Ranvier^" has pointed out, are not to 

 confused with pseudopodia. Besides the quaint fixed finely 

 mular excrescences there are protruded from the cell at a slightly 

 xwer temperature, quickly rising, clearer, vesicular-looking pro- 

 jsses; these are thrust out in succession from various points of the 

 jriphery, one falling as a later rises. They lead to no locomotion of 

 cell. I mention them here because I have never seen the coarsely 

 inular leucocyte or the hyaline leucocytes produce either of these 

 excrescences, although under the same conditions, and in the same 



* ' Kern u. Protoplasma/ Leipzig, 1892. 



t ' Proc. Internal. Congress of Physiologists,' Lige, 1892. 



J ' Arch. f. d. Physiologic,' 1879 ; ' Zeitsch. f . klin. Medicin,' 1880 ; later papers 



Op. tit. 



]| Loo. tit. 



IT "Traite Technique d'Histologie,' p. 156. 



