434 Dr. L. Brunton and Mr. S. Delepine. Changes [Apr. L' 



B. Liver of small size with only a few psorospermic lesions. 

 Liver cells medium sized. 



Outline of cells and mitoma indistiuct (i.e., normal in appearance). 

 Meshes of the mitoma small, normal in appearance. 

 Bile canaliculi, main and lateral, very distinct. 

 Glycogen reaction doubtful, diffuse, normal. 

 Sugar produced in 24 hrs. post mort. a little more than normal. 

 reaction slight and round hepatic veins, i.e., normal. 



C. Aniline in this case does not seem to have produced any marked 

 effect on the liver. 



Action of Phenol on a Fasting Liver. 



A. Last food given 25 hrs. before death. 



Rectal injection of 0'83 gram (about 12 grains) of absolute phenol 

 ' dissolved in 10 c.c. of water 46 mins. before death. 



B. Moderate amount of psorospermic lesions. 

 Liver moderately large. 

 Cells small, but not below normal. 



Mitoma and outline of cells indistinct, but not more so than 

 normal. 



Meshes of mitoma generally small, irregular. 



Glycogen reaction indistinct, about normal. 



Sugar produced in 24 hrs. post mort. very slightly increased. 



Iron reactions not very distinct, altered. 



C. Phenol does not seem in this case to produce marked alterations 

 of secretory activity. 



Note. The cells are in many places much vacuolated, breaking 

 down, and probably in a state of incipient necrosis. 



Action of Phenol on a Fed Rabbit. 



A. Time of last meal, 7 hrs. 15 mins. before death. 

 0'5 gram (about 7| grains) of phenol dissolved in 10 c.c. of water 

 injected into the rectum 50 mins. before death. 



B. Psorospermic lesions of the liver moderately abundant. 



Organ large. 



Cells large. 



Outline of cells and mitoma clear, but less so than normal. 



Size of the meshes of the mitoma a little less than normal. 



Bile canaliculi generally indistinct. 



Glycogen reaction much diminished and diffuse. 



