The 



/// tin' 



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Wagner, Or. Quoted by K. F. Smith in ' Spread of Plant Disease.-.' 



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" The Micro-organism of Distemper in the I .)o<>-, and the Production 

 of a Distemper Vaccine." By S. MONCKTON COPEMAN, M.A., 

 M.D., F.It.C.P. Coinnuuiicated !>y Sir M. FOSTKI;. Sec. U.S. 

 Ifeceived November 14, Read December (i, 1900. 



(From the Brown Institution.) 



Distemper is so fatal a disease of dogs, more particularly of such as 

 are highly bred, that a method of preventing invasion by the disease 

 has always been a desideratum. 



As the result of investigations into the bacteriology of this disease, 

 carried out in continuance of those commenced in my laboratory at 

 St. Thomas's Hospital about ten years ago by the late Everett Millais, 

 I find that the specific micro-organism concerned is a small cocco- 

 bacillus, which stains with the ordinary aniline dyes, but is decolorised 

 by the method of (.Ti-a-m. It grows readily on the surface of agar at 

 body temperature the individual colonies when isolated by the method 

 of plate-culture having a greyish, glistening, semi-translucent appear- 

 ance by reflected light, and a light-brownish tint by transmitted light. 

 The general form is circular, but occasionally, and specially in primary 

 growths, the edge is somewhat irregular. The microbe also grows well 

 in beef-broth, causing at first a general turbidity. Later on, a deposit 

 falls to the bottom of the tube, and the supernatant liquid becomes 

 somewhat clearer. In cover-glass preparations from broth cultures 

 the bacilli are not unfrequently found united together to form chains, 

 sometimes of considerable length. The bacillus is capable of growing, 



