134 Obituary Notices of Fellows deceased. 



circulation in the brain, on the specific gravity of the blood, on 

 the causation of "shock," on mechanisms protective against infection, 

 on the seat of the formation of haemoglobin, on phagocytosis; in all 

 these he was, if not the initiative spirit, a participant and adviser, 

 evincing always the keenest and most sympathetic interest. His 

 interest in biology was strikingly catholic, but problems dealing with 

 the circulation had paramount attraction for him. Encouragement 

 to devote attention to the clinical aspect of that field was given him 

 by his colleague, Clifford Allbutt, the Regius Professor of Physic. 

 In 1892 appeared, in the " Philosophical Transactions," the long work 

 on the mammalian heart carried out with Professor Adami. Instru- 

 ments were to a large extent specially devised for this research. The 

 cardiac plethysmograph and the cardio-myograph were each examples 

 of ingenuity that never failed to meet with resource the mechanical 

 difficulties of a subject numerously beset by them. 



Roy entered upon pathology at a time when advance in bacterio- 

 logical methods was opening to it new fields for investigation in 

 regard to the diseases of infection and their remedy. He welcomed 

 this new line of inquiry with characteristic readiness, and at once felt 

 its coming value. But the somewhat monotonous kind of labour 

 involved in this class of investigation was tedious to him to a degree 

 unexperienced by less rapid and less impulsive workers. He, how- 

 ever, contributed to such investigations. When Professor Superin- 

 tendent of the Brown Institution he was commissioned to investigate 

 in the Argentine Republic a disease which was devastating the herds 

 in the province of Entre Rios. He succeeded in devising a preventive 

 inoculation which alleviated the mischief. In 1885, Asiatic cholera 

 having appeared in a very severe epidemic form in Spain, he, with 

 Graham-Brown and Sherrington, investigated the bacteriology of 

 the epidemic throughout the summer and autumn of that year. The 

 work was one of the earlier confirmations of Professor Koch's dis- 

 covery of the cholera-spirillum as the concomitant of the disease. 

 In evidence of his sterling enthusiasm for this branch of his science, 

 it may be recalled that Roy was one of the earliest, perhaps the 

 earliest, to start and urge forward the movement which has resulted in 

 the foundation of the " Jenner Institute." 



His death at the early age of forty-three came somewhat suddenly, 

 though after complete nervous breakdown had for three years 

 removed him from scientific work. In 1887 he married Violet, 

 daughter of Sir George Paget, the late Regius Professor of Physic 

 .at Cambridge. 



A man of strong convictions, almost impetuous in his determination 

 to act upon them, Roy as a pathologist had the firm belief that the 

 future of pathology lay along the same lines of advance as physiology 



