1884.] Ingesta and Egesta of Mr. E. P. Weston. 53 



added together, and then the days arranged in order, show a very 

 remarkable coincidence as follows, and renders it in the highest 

 degree probable that the greater or less excretion of sulphates 

 depended in Weston's case on the amount of bread-stuffs consumed. 



Ingestion of Sulphur 



bread-stuffs. excretion. 



Friday Friday 



Wednesday Wednesday 



Saturday Saturday 



Tuesday Tuesday 



Monday Thursday 



Thursday Monday 



Note on the Urine Alkaloids. 



The alkaloids of the urine, especially kreatinine, have been 

 variously considered as derived from metabolism of the living muscle, 

 or from nitrogenous food. It is instructive to observe that the 

 urine alkaloids in Weston's case were in excess on Monday, a day 

 which followed twenty-four hours of complete rest, while during the 

 rest of the week save Saturday, the amounts were rather below 

 normal, the days arranged in series of most alkaloid down to least 

 alkaloid are Monday, Saturday, Friday, Tuesday, Wednesday, Thurs- 

 day, and this series shows no agreement with either the meat ingested 

 or the broth. It would, therefore, seem that exertion, so far from 

 increasing the excretion of the flesh bases, oxidises them up probably 

 to urea. 



Faeces. 



The solid excreta for the five days, Tuesday to Saturday inclusive, 

 were mixed as thoroughly as possible, and analysed as follows : 



A weighed portion was digested with strong alcohol to remove as 

 much of the water as possible, the dehydrated residue was then 

 exhausted in a Soxhlet's apparatus by ether ; the alcoholic and 

 ethereal extracts were united, dried, and weighed ; the exhausted 

 residue was also dried and weighed ; the difference between the sum 

 of these weights and the original was taken as representing the 

 water. I may remark that I have always found the method detailed 

 give more constant results than drying in the usual way. 



The fat and cholesterin were extracted from a weighed portion by 

 ether-alcohol, the volatile solvents being driven off, the extract was 

 dried, redissolved by anhydrous ether-alcohol, and on evaporation 

 weighed as fat and cholesterin ; subsequently the cholesterin was 

 extracted by saponifying the fat, and treating the soap with ether. 



