Action on Staphylococcus pyogenes ~by Human Blood, etc. 147 



and therefore presumably of its own, a toxin which would cause 

 necrosis in the mucous membrane of its own stomach were it not 

 for some deterring influence, probably the concomitant formation of an 

 anti-immune body. 



REFERENCES. 



Theohari et Babes. " Note sur une Gastrotoxine," ' Compt. rend, de la Soc. de 



Biol.,' 1903, No. 13. 



Yon Dungern .... ' Munich Med. Wochensclirift,' 1899. 

 Moxfcer ' Deutsche Med. Wochenschrift,' 1900. 



" On the Action exerted upon the Staphylococcus pyogenes by 

 Human Blood Fluids, and on the Elaboration of Protective 

 Elements in the Human Organism in Kesponse to Inoculations 

 of a Staphylococcus Vaccine." By A. E. WRIGHT, M.D., late 

 Professor of Pathology, Army Medical School, Netley, Patho- 

 logist to St. Mary's Hospital, Paddington, W., and STEWART 

 E. DOUGLAS, M.R.C.S., Captain, Indian Medical Service. 

 Communicated by Sir J. BURDON SANDERSON, Bart., F.RS. 

 Eeceived July 26, 1904. 



(From the Pathological Laboratory of St. Mary's Hospital, London, W.) 



The subject matter with which we have here to deal may be 

 distributed under the following heading? : 



(1) Determination of the nature of the action which is exerted upon 

 the Staphylococcus pyogenes by normal human blood fluids, and by the 

 blood fluids of patients who have been inoculated with a Staphylococcus 

 vaccine. 



(2) Comparison of the phagocytic power of the subjects of Staphy- 

 lococcus invasion with the phagocytic power of normal individuals. 



(3) Distribution in the infected organism of the opsonins which here 

 come into consideration. 



(4) Determination of the question as to whether the opsonins are 

 present in the blood of the infant at birth. 



(5) Determination of the course of the reaction of immunisation 

 which supervenes upon the inoculation of a Staphylococcus vaccine. 



(1) Nature of the Action which is exerted upon the Staphylococcus pyogenes 

 by Normal Blood Fluids, and by the Blood Fluids of Patient 

 Inoculated with a Staphylococcus Vaccine. 



Bactericidal Action. It was shown in the course of the classical 

 researches on the bactericidal power of the blood which were conducted 



VOL. LXXIV. M 



