424 



Mrs. A. M. Waller. On the "Blaze-currents" [Dec. 1, 



Liver (March 24). 

 Strength of excitation. Response. Electrodes. 



5000 -- +0-0010 10000+ = 0-0001 



+ -0-0009 

 10000+ -0-0013 +0-0002 

 + 0-0022 



- = 0-0001 



Liver. 



5000 - + 0-0047 Response 

 + + 0-0053 surface 

 to hilum 



1 hour later 



10000+ -0-0047 +0-0002 

 - +0-0047 -0-0003 



Electrodes 



placed on 



surface 



and hilum 



Remaining and slowly sub- 

 siding. 



The gall bladder invariably gives an antidrome " blaze " or response 

 to excitation ; it is an instance of the equivocal blaze current, in the 

 contrary direction to the exciting current, described by Waller in 

 vol. 68, p. 79, ' Proc. Roy. Soc.' Weak stimulus elicits one antidrome 

 blaze ; to stronger stimulus the response may be triphasic ; antidrome, 

 homodrome, antidrome. The first and antidrome response is a large 

 effect and soon over, the galvanometer spot flies off and quickly 

 returns to zero and beyond, indicating the second and homodrome 

 effect, which is a prolonged change lasting about two minutes and slowly 

 subsiding, the second effect is often larger than the first. 



The blaze is a local effect, as shown in experiment on March 22, 

 where it is abolished by strong tetanus at one spot, but found to persist 

 in other parts on turning the bladder round. 



The blaze is abolished by boiling the gall bladder or by subjecting it 

 to strong chloroform vapour, or by tetanus. 





