THE LARGE INTESTINE. 



1659 



numerous in the caecum, and especially in the vermiform appendix, in which the 

 nodules are so plentiful that they form in places almost a continuous mass of lymphoid 



tissue. The solitary follicles are less fre- 



FIG. 1408. quent in the colon, but are again numer- 



ous in the rectum. They are generally 

 of larger size than in the small intestine, 

 measuring from 1.5-3 mm. in diameter, 

 and are situated at the bottom of pit-like 

 depressions on the mucous surface into 

 which the nodules project. 



The submucous coat closely cor- 

 responds with the similar areolar tunic of 

 the small intestine, allowing of fairly free 



FIG. 1409. 



Portion of mucosa of large intestine, showing Lie- 

 berkuhn's glands cut lengthwise ; many epithelial ele- 

 ments contain mucus and are " goblet-cells." X 225. 



FIG. 1410. 



Mucosa of large intestine sectioned parallel to free 

 surface, showing Lieberktihn's glands cut crosswise; 



lands separated by intervening stroma of mucous mem- 

 rane. X 225. 



FIG. 1411. 



r Peritoneal coat 



3 Adipose tissue 



A'ein 



Artery 



Portion of descending colon, somewhat distended, show- Longitudinal section of epiploic appendage. X 23. 



ing sacculations, taenia, and epiploic appendages. 



play of the mucosa. In addition to the blood-vessels, lymphatics, and nerve-plexus 

 of Meissner, it contains the deeper and more expanded parts of the solitary nodules. 



