no CLINICAL VETKRINAKV MKDICINK AND SURC.ERV. 



a part of its food, the condition suddenly became aggravated. The 

 horse was found stretched on the ground, the face drawn, the respira- 

 tion very rapid, dyspncea marked, and the mucous membrane C}anotic. 

 It rose with much difficult}-, but almost immediately fell again, and 

 struggled violently. The dyspncea became more and more marked : 

 the animal broke out in perspiration ; the limbs became cold ; and 

 death followed. 



Autopsy. — Lesions of asphyxia : mucous membranes cyanotic; mus- 

 cular tissues deep red in colour ; the capillaries of the subcutaneous 

 cellular tissue engorged with blackish liquid blood, which turned red 

 and coagulated rapidly on contact with air ; viscera congested ; patches 

 of ecchymosis in the lungs, cavities of the heart, and under the endo- 

 cardium. 



The new growth was more generalised than had been suspected 

 during life. Tumours existed in very large numbers. Some were 

 globular ; the greater number flattened ; a few thinner at the centre 

 than at the periphery. Their dimensions varied between those of a pea 

 and of a child's head. All were sharply circumscribed ; all de\eloped 

 in the connective tissue — the majority in the subcutaneous connective 

 tissue, — some under the serous membranes, and in the muscular inter- 

 stices. Sections through muscles failed to reveal any in the muscular 

 trssue itself. The majority of these tumours, especially those of small 

 size, or recent formation, had produced no change in the surrounding 

 tissues. Others had caused inflamrhation as indicated by sclerosis, or 

 the formation of a fibrous limiting membrane : others, again, were sur- 

 rounded by a gelatinous yellowish or blood-stained exudate. Their 

 physical characters and structure varied according to their age. The 

 smaller, or more recent, were soft and friable, formed of a homo- 

 geneous whitish tissue ; others, of larger size and firmer consistence, 

 were greyish towards the centre ; in the largest, three concentric 

 zones could be distinguished — an external friable zone, light in colour, 

 resembling in structure the recent tumours ; a middle, greyish ; finally, 

 a central, light yellow in colour and irregularly defined, formed by 

 broken-down tissue. The superficial layers of many of these new 

 growths showed fine ecchymoses. 



In the left hind leg, between the muscular portion of the short 

 adductor, the pectineus and the adductors of the thigh, was a tumour 

 weighing jf lbs. ; above the right shoulder, under the cervical trapezius 

 and the rhomboideus, another, weighing 252 oz. ; behind this shoulder, 

 between the great serratus and great dorsal muscle, still another, more 

 than 21 oz. in weight. 



We counted fift\- between the muscles of the right arm and the 



