112 CLINICAL VETERINARY MEDICINE AND SURGERY. 



occupying the periphery, a denser greyish tissue the intermediate part, 

 and yellowish irregularly-defined patches the centre. The two former 

 zones were marked with numerous hsemorrhagic points. The pneumo- 

 gastric nerves were surrounded by the peripheral layer of this tumour. 



The submaxillary and tracheo-bronchial lymphatic glands were 

 slightly enlarged, but not in consequence of sarcomatous growths. 

 The sublumbar, inguinal, and prepectoral glands were healthy, despite 

 the fact that lymph from highly infected regions passed through them. 

 Nothing whatever in the nervous centres. 



Four days before death examination of the blood had shown a 

 proportion of 4,562,750 red blood-corpuscles to 12,918 leucocytes per 

 cubic millimetre, i. e. one white corpuscle to 353 red. Generalisation 

 of the sarcomatous process had, therefore, been followed by marked 

 leucocvtosis. 



There, then, you have a very exact and detailed description of this 

 peculiar case. 



I have said that to the naked eye and under the microscope these 

 tumours showed the appearances of sarcomata ; but of what variety ? 

 You know that four principal kinds are distinguished : (i) encephaloid 

 or globo-cellular sarcoma, formed of round-cells with large nuclei and 

 scanty protoplasm, interspersed with thin-walled embryonic blood- 

 vessels ; (2) fasciculated or fuso-cellular sarcoma, formed of elongated 

 fusiform cells and blood-vessels, resembling those just mentioned ; 

 (3) myeloid sarcoma, a new growth affecting bony tissue, in which 

 large multi-nucleated cells resembling the myeloplaxes of bone-marrow 

 predominate ; (4) and finally, melanotic sarcoma, the tumour of white 

 horses, in which the cells are full of grey or black pigment granules. 



The tumours in our patient did not belong to any of these varieties. 

 They were formed of cells of unequal size, the majority rounded, but 

 some irregular, and of vessels without clearly-defined walls. In addi- 

 tion we detected a reticulum, varying in thickness according to the 

 points examined and the age of the tumours. 



In recent tumours all the cells were round, while the reticulum was 

 delicate and scanty, though quite clear in sections which had been 

 carefully manipulated with a brush. In the larger, older, and there- 

 fore harder tumours, a certain number of the cells were irregular or 

 fusiform, and the reticulum more abundant, forming at certain points 

 narrow interlacing bands. Their histological characters placed these 

 tumours between the sarcomata and lymphadenomata ; they were 

 lymphoid or lymphadenomatous sarcomata. 



