TUBERCULOSIS IN THE HORSE. 23 1 



similar case. Multiple and bilateral swelling of lymphatic glands may 

 at first glance suggest lymphangitis. 



At a varying but usually late stage in the disease most patients 

 show abundant polyuria, followed by rapid wasting, a fact to which 

 M. Nocard called attention ten years ago in an " Etude clinique de la 

 Phthisic tuberculeuse du Cheval." The urine contains large quanti- 

 ties of urea and uric acid. 



In the horse tuberculosis usually follows a very slow course, certain 

 patients continuing work for months, or even years, and showing little 

 tendency to emaciation or to febrile attacks. The changes may long 

 remain localised in the abdominal glands, but finally the subjects 

 either become very feeble or the bacilli enter the venous circulation, 

 causing general infection. Febrile symptoms are then seen. The tempe- 

 rature rises to 40° C. or 40-5° C. (104° F. or 104*9° F-)> and wasting 

 makes rapid strides. Sometimes the hind limbs become swollen. 



In the horse tuberculosis may also assume unusual forms, liable to 

 be mistaken for other diseases, which differ so widely from classical 

 types as not even to suggest the idea of tuberculous infection. I will 

 describe two cases from my own clinique. 



The first was that of an eight-year-old horse brought for examina- 

 tion in April, i88g, by a contractor who had bought it three years 

 before. Different points on the surface of the body showed indolent 

 tumours of fibrous consistence and varying size, the largest about the 

 diameter of a two-shilling piece and the thickness of a man's little 

 finger. Some had developed in the skin, others in the subcutaneous 

 connective tissue ; both varieties were accompanied by disease of 

 lymphatic glands. At certain points the largest swellings were con- 

 nected with neighbouring lymphatic glands by corded lymph vessels. 



The patient was left here for more thorough examination. Rectal 

 exploration revealed nothing. The temperature oscillated between 

 39° C. and 39'5° C. (102*2° F. and 103*1° F.). The urine was of 

 normal amount, but slightly albuminous. The proportion of red and 

 white blood-corpuscles was normal. One of the subcutaneous swellings 

 was excised for histological study. Its structure was that of a sarcoma. 

 The horse was removed home and put to work, but grew more and 

 more feeble. At a trot its breathing became steadily aggravated, and 

 a loud roaring sound was produced. Certain tumours diminished and 

 disappeared, but many others developed. Having become incapable 

 of work the animal was slaughtered. On post-mortem examination we 

 found numerous swellings in the skin and subcutaneous connective 

 tissue, together with neoplastic and sclerosing infiltration of certain 



