302 CLINICAL VETERINARY MEDICINE AND SURGERY. 



several times during the evening showed signs of violent excitement. 

 Next day she had regained her usual condition. 



A fortnight later fresh attacks occurred without any evident cause. 

 When they came on, the patient, if standing, was taken with cramp ; 

 the fore-limbs were stretched out to their fullest extent, then the hind 

 limbs collapsed ; the animal fell towards the left and remained pros- 

 trate, the entire body trembling; sometimes she howled as though in 

 pain. During these attacks, which lasted from ten minutes to a 

 quarter of an hour, the head was strongly inclined to the left. 



Towards the end of September the disease became aggravated ; the 

 appetite, which had previously been good, graduall}- diminished, the 

 animal remaining for whole days without taking food. She no longer 

 barked ; urine and faeces were passed in her kennel. During the night 

 she often seemed subject to great excitement. Nevertheless on certain 

 days the disturbance was much less marked. One morning she was 

 walked nearly two miles without showing unsteadiness, without 

 stopping, and without any apparent disturbance of movement. 



Such was the history given when the animal was brought here. 



She was left in hospital. The sjmiptoms noted on the first exami- 

 nation were as follows : — The face was dull and expressionless ; the 

 animal reeled on her limbs ; movements were slow and irregular ; the 

 fore-limbs showed irregular contractions ; the head was extended on 

 the neck, and inclined towards the ground or to the left ; the back was 

 arched. Sometimes the animal walked in circles towards the right ; 

 at times the hind limbs collapsed, the animal fell towards the left, and 

 had great difficulty in rising. The respiration was painful and catch- 

 ing, the circulation slightly accelerated. Examination of the head 

 revealed nothing particular except inequality of the pupils, the left 

 being larger than the right. Sensation was normal. Temperature 

 39'5° to 39-8" C. 



During the first few days the patient still ate a considerable portion 

 of her food. Twelve grains of iodide of potash were given daily. After 

 a short time she would only take a few spoonfuls of milk. She remained 

 lying quietly in her kennel, occasionally lifting her head and whining. 

 Death occurred on the 14th October. 



Autopsy. — The lungs showed numerous tumours, the majority the 

 size of a hazel-nut, but some as large as a walnut. These were whitish 

 in colour, sharply delimited, and consisted of a friable tissue, generally 

 light in colour, though reddish in places. Some contained a central 

 cavity filled with liquid. 



The external appearance of the brain was at first sight normal. On 

 more attentive examination a greyish area, which showed up clearly 

 against the neighbouring parts, was noted in the anterior half of the 

 right hemisphere. On incising this part a little greyish liquid exuded. 

 An ovoid tumour, measuring one inch and a quarter from before back- 

 wards and three quarters of an inch across, had developed in the wall 

 of the hemisphere. Its periphery was sharply defined, and its centre 

 had undergone transformation into a cyst ; its tissue appeared reddish 

 grey. 



No new growth of any kind was found in the neighbourhood of the 

 scars resulting from removal of the mammary tumours. 



