39° CLINICAL VETERINARY MEDICINE AND SURGERY. 



swelling was noted on the left side of the lumbar region ; and another 

 hard, rounded, very large swelling on the left side of the inferior 

 abdominal region. The abdomen was enormous, and the back was 

 depressed. Temperature 39'4° C, pulse 170. The respiration, 

 though only slightly accelerated (25 per minute), was irregular and 

 discordant. The animal had shivering fits and muscular tremors. On 

 percussion the entire depth of both pulmonary lobes showed partial 

 dulness. 



Diagnosis. — Malignant tumour in course of generalisation. 



During the following days no notable change occurred. The urine 

 was a little darker than normal, and albuminous. It contained glucose 

 or bile pigment. Nothing could be detected on rectal exploration. 

 On counting the blood-corpuscles a cubic millimetre was calculated to 

 contain — 



Red blood-corpuscles .... 8,215,875 

 White blood-corpuscles . . . 19,058 



That is a proportion of 430 to i. 



The owner was informed that recovery could not be expected. 

 Being handed over to us, the dog was kept until the 19th May. The 

 tumours on the back and in the abdominal region increased in size, 

 and the animal gradually became thinner until the day of death. 



Autopsy. — Extreme wasting. On removing the skin covering the 

 dorsal region an ovoid, lobulated tumour, as large as a man's fist, was 

 found in the longissimus dorsi muscle, which at this point had almost 

 entirely disappeared. 



The left kidney was transformed into an irregular, ovoid, bosselated, 

 obscurely fluctuating tumour, the size of a man's head. It was sus- 

 pended by a peduncle, and floated in the abdominal cavity, adhering 

 to the epiploon. On incision a brownish-red liquid escaped. After 

 escape of liquid the growth weighed thirty-five ounces. The pelvis of 

 the kidney was very large, irregular in shape, and lined with inflamed 

 mucous membrane. An inch from the depression, which represented 

 the hilum, the ureter was obliterated and atrophied. 



The lower portion of the left lobe of the liver was deformed by a 

 soft, fluctuating tumour, the size of a man's fist. Incision gave exit to 

 a brownish liquid. The right lobe contained a tumour as large as a 

 hazel nut, similar in appearance to the preceding, but which had not 

 undergone softening. 



On opening the thoracic cavity a new growth, as large as a pigeon's 

 egg, was seen under the vertebral column, immediately in front of the 

 diaphragm. The lungs were covered with mammilated tumours of 

 varying dimensions and appearance, the largest the size of a hazel nut. 

 Nearly 200 were counted on the different lobes, and sections revealed 

 hundreds more in the depths. All these new growths showed the same 

 macroscopic character ; their tissue was greyish, friable, and full of 

 liquid. The bronchial lymphatic glands were somewhat swollen. 



On microscopic examination these tumours appeared formed by 

 delicate connective-tissue bands surrounding alveoli filled with epi- 

 thelial cells, usually of small dimensions. 



