DISEASED PROSTATE IN THE DOG. 39 1 



Inoculation Test on Two Dogs. — The tumour developed in the longis- 

 simus dorsi muscle was kept in the incubator at ^y° C. until the 

 moment of inoculation. In the first dog the lumbar region was shaved 

 and rendered aseptic. An incision, about an inch in length, was then 

 made through the skin, the longissimus dorsi divided after displacing 

 the skin, a fragment of the cancerous tissue inserted at the base of the 

 muscular incision, and the skin allowed to return to its first position. 

 The wound was sutured with silk and covered with collodion. In the 

 second animal the fragment of cancerous tissue was placed in the sub- 

 cutaneous connective tissue. 



Next day the surroundings of the wound were slightly swollen. No 

 suppuration occurred. 



These inoculations remained sterile. The swelling they produced 

 gradually diminished, and disappeared entirely during the course of 

 the third week. 



[A case of carcinoma of the kidney is described in section VII here- 

 after.] 



DISEASED PROSTATE IN THE DOG. 



loi. Eight-year-old bull-dog, weighing 45 lbs. 



History. — The development of disease was gradual and very ill- 

 defined. Structural changes had occurred long before symptoms 

 drew attention to them. During 1894 had several attacks of constipa- 

 tion, accompanied by slight prominence of the anus ; but no marked 

 symptoms occurred until three months before death. An attack 

 accompanied by much straining, apparently due to impaction of faeces, 

 then occurred, but after administration of enemata with a long tube 

 suspicion arose of other complications, and careful examination revealed 

 the condition of the urinary organs. 



State on Examination. — With the abdomen relaxed and a finger in 

 the rectum the pelvic swelling could be well defined, and was obviously 

 either a prostatic tumour or a stone impacted near the neck of the 

 bladder. A limited area of the tumour was calcified, and through the 

 abdominal wall it felt exactly like a stone about the size of a small 

 walnut, connected with the bladder and fixed to it, but not to the spine 

 or pelvis, except to the extent to which the bladder and prostate were 

 fixed. An impacted stone producing much inflammatory thickening 

 and a partially calcified prostatic tumour would obviously have presented 

 similar or identical symptoms ; the latter hypothesis was thought the 

 more probable, but the former was not altogether excluded. The bladder 

 was greatly distended, as was to be expected ; but there were peculiar 

 features. In shape it was very much elongated in proportion to its 

 breadth, passing high up into the abdomen, and its contour was 

 broken by a slight constriction a little above the middle, giving it 

 somewhat of an hour-glass shape ; it was not clear at first whether this 

 constriction was due to some fibrous band engaging the bladder itself, 

 or to a partial interval between a distended bladder and a dilated 

 kidney ; but the question was settled by emptying the bladder with a 

 catheter, when it was found only the lower part of the tumour was 

 reduced, and that a soft fluctuating tumour remained in the left lumbar 



