428 CLINICAL VETERINARY MEDICINE AND SURGERY. 



per cent, solution of iodine tincture. On the eschars separating, the 

 wounds appeared healthy and covered with tine granulations. The 

 horse was returned to work. 



The wounds did not completely heal, and the granulations soon 

 projected more than three eighths of an inch above the level of the 

 skin. Gradually the tail became swollen, its base doubling in size in 

 six weeks ; the swelling extended to the upper part of the croup, in 

 which region numerous subcutaneous tumours developed. The animal 

 showed symptoms indicating generalisation of the new growth, gradu- 

 ally fell away in condition, and had to be slaughtered. 



Autopsy. — The tail was of enormous size, asymmetrical at its base, 

 the left half being larger than the right. On the left side, a hand's 

 breadth from the anus, was a large mammillated patch, from which the 

 hair had fallen, formed by the confluence of several tumours ; it 

 extended to both the upper and lower surfaces of the tail. Several 

 small tumours were included within its area. The base of the tail was 

 everywhere invaded ; the skin and connective tissue being very 

 markedly thickened. The muscles were whitish, hard, and sclerosed. 



In the subcutaneous connective tissue of the croup and upper part 

 of the quarters, numerous rounded, slightly flattened, tumours were 

 found, the largest the size of a two-shilling piece. Most of the 

 muscles in these regions were hardened or destroyed by the new 

 growths. The spleen was enlarged and bosselated on both surfaces, 

 in consequence of the growth of yellowish-white tumours, varying in 

 size between a hazel-nut and a man's fist : the centres of some of these 

 tumours were slightly depressed. The liver was hypertrophied, and 

 contained many small tumours, resembling those above described. 

 The surface of the lungs showed numerous whitish nodules, and sec- 

 tions displayed a dozen tumours as large as a man's fist. 



On microscopic examination the tumours in the tail, muscles, and 

 viscera showed the characters of encephaloid cancer. Their tissue 

 consisted of a stroma arranged in tracts, surrounding spaces filled with 

 epithelial cells. Blood-vessels were numerous. Sections of the 

 tumours from the tail showed in places hsemorrhagic centres. 



Remark. — The inflammation caused by excision and cauterisation 

 had provoked rapid diffusion of the new growths. 



