468 CLINICAL VETERINARY MEDICINE AND SURGERY. 



from the epiploon, the following animals were intra-peritoneally 

 injected : — a dog (5 cubic centimetres), a rabbit (2 cubic centimetres), 

 two guinea-pigs (i cubic centimetre), and two fowls (2 cubic centi- 

 metres). 



The dog was killed on the 2gth July, forty-seven days later. 



Atiiopsy. — Numerous granulations on the peritoneum and epiploon. 

 The latter was greatly indurated, being as thick as a man's hand in the 

 neighbourhood of the spleen. Enlargement of the mesenteric, medias- 

 tinal, and tracheo-bronchial glands. Granulations in the liver and 

 lung. 



The rabbit died on the 25th September, 104 days after inoculation. 



Autopsy. — Generalised tuberculosis. Enormous lesions in the peri- 

 toneum, epiploon, mesenteric glands, kidneys, testicle, and prostate. 



One of the guinea-pigs died on the 25th June, after thirteen days. 

 Bacteriological examination of the pulp of the liver and spleen 

 revealed the presence of bacilli in these organs. 



The other died on the 4th July, after twenty-two days. It was 

 already much wasted, and showed lesions of tuberculosis in course of 

 generalisation, — fine granulations in the peritoneum, hypertrophy of 

 the epiploon, and granulations in the kidney and spleen, which last 

 was five times its normal size. Two other guinea-pigs were injected 

 with an emulsion prepared by crushing a little spleen pulp in sterilised 

 water. The first died on the ist October, after eighty-nine days ; the 

 other on the 13th October, after loi days. Both showed on post-mortem 

 generalised lesions with enormous enlargement of the spleen. 



The fowls were killed on the i6th June, 1898, after two years and 

 four months. No tuberculous lesion was found on post-mortem. 



165. A ten-year-old grey cart mare, seen on the 8th January, 

 1898. 



History. — During the last week of December, 1897, this animal 

 appeared dull, unwell, and was not feeding. Several other horses 

 in the stable were not thriving or eating well, but the above animal was 

 the worst, and while medical treatment and better food improved the 

 others this mare remained unaffected. There were no acute S3'mptoms, 

 but the disease appeared indefinite, chronic, and progressive. 



State on Examination. — Appeared in fair condition, and at first sight 

 showed no disquieting symptoms. Pulse 56 and of fair strength ; 

 respirations 25 ; temperature 103° F. Auscultation of the chest 

 revealed a harsh respiratory murmur, indistinct towards the lower 

 part ; percussion everywhere indicated increased dulness, which towards 

 the floor of the chest was almost absolute. Cough was almost com- 

 pletely absent. 



Apart from the history of gradual onset and the comparatively 

 slight fever and injection of the conjunctivae this case might have been 

 mistaken for influenza with supervening pneumonia. The symptoms 

 failed to indicate the rapidity with which the disease was progressing 

 until shortly before death on the 19th January. 



Post-mortem Examination. — The lungs alone were diseased. The 

 pleurae were healthy, but the lungs on removal were very heavy and 



