4^2 



CLINICAL VETERINARY MEDICINE AND SURGERY. 



the day. Administration of the first dose of quinine was followed by a 

 depression of temperature, which reached its maximum (i"4° C.) at the 

 end of an hour. Two hours later the temperature had risen to its 



Chart I. — The dark vertical lines indicate the time at which quinine was given. 



former point. After administration of the second dose the temperature 

 fell six tenths of a degree C. in two hours ; but two hours later it had 

 returned to 40*2° C, only two tenths below the first reading (Chart i). 

 On the 22nd the animal's state was little changed. Respirations 

 28, pulse 68, temperature 40*5° C. A little rusty discharge from both 

 nostrils and some crepitant rales on auscultation. The first dose of 

 quinine again lowered the temperature eight tenths of a degree in two 



Chart II. 



hours ; but the curve afterwards rose, returning in two hours to its 

 former height (40*5° C). The second dose was followed an hour after 

 administration by a rise of two tenths of a degree ; three hours later 



