PNEUMONIA. 



485 



and a half drachms of quinine sulphate were given in electuary. At 11.30 

 the temperature was 40*3° C, at midday 40*5° C, at i o clock 40*8° C, 

 at 2 o'clock 40'3° C. In three hours the temperature had risen i'2° C. 

 Concurrently with this rise in temperature excitement had been shown 

 during the first two hours. There was anxiety, trembling, marked 

 acceleration of breathing, and excessive dilatation of the nostrils. 

 After the first two hours the temperature gradually decreased. At 3 

 o'clock it became 40*9° C. The second dose of electuary was given. 

 During the following hour the temperature continued to fall. At 3.30 

 it was 40*5° C, at 4 p.m. 39*6° C. From 4 p.m. until 6 p.m. it rose 

 three tenths of a degree (Chart 5). 



Next day the general condition was stationary, the disease taking 

 its usual course. Temperature 39*9° C. ; respiration 18; pulse 60. 

 The pulse was small; the conjunctiva remained injected. On aus- 

 cultation the respiratory murmur was markedly diminished in the 

 lower part of the right lung, which was also dull on percussion. Over 

 the upper part of this lobe, and the whole of the left lung, the vesi- 



Chart VI. 



cular murmur was exaggerated. The cough was rough, deep, and 

 sometimes paroxysmal. An abundant rust-coloured discharge ran 

 from both nostrils. 



As on the previous days the animal received three and a half ounces 

 of sodium bicarbonate and five drachms of quinine sulphate in two 

 doses. The temperature curve on that day closely resembled the first. 

 The first dose of quinine was followed by a rise in temperature of 

 i'3° C. in four hours. At three o'clock the temperature was 40*6° C. 

 A second dose of quinine sulphate was given. An hour later the 

 temperature fell to 39*8° C, but the depression was not maintained, for 

 at seven p.m. the temperature marked 40*4" C. (Chart 6). The excite- 

 ment, rigors, and trembling fits noted on the previous day were re- 

 peated. 



On the 28th the morning temperature was 40*6° C, the pulse 80, 

 and the respirations 25. The pulse was feeble, respiration painful, 

 and expiration double. The cough still remained frequent and paroxys- 

 mal, and the rust-coloured discharge was somewhat free. Percussion 



