502 CLINICAL VETERINARY MEDICINE AND SURGERY. 



On the 23rd the contractions and trismus had become still more 

 exaggerated. Swallowing was impossible. The same treatment was 

 continued, but the animal died during the night. 



Autopsy. —Lesions of asphyxia. 



195. A nine-year-old gelding, entered hospital May 6th, 1899, 

 having shown symptoms of tetanus for two days previously. Came 

 from the eastern suburbs of Paris. A month before had fallen and 

 injured its knees. 



State on Examination. — The legs were stiff and placed farther apart 

 than usual ; the head was extended on the neck. The animal had 

 relatively little difficulty in moving. The face appeared anxious ; the 

 eyes were fixed, the nostrils dilated, the ears drawn together and rigid ; 

 the tail was lifted. The least excitement caused the membrana 

 nictitans to be projected over the eye. Mastication was slow, and 

 appetite diminished; trismus was little marked. The front of the left 

 knee showed a circular wound the size of a sixpence. Temperature 

 38*8° to 39'i° C. ; respiration 28 to 30 ; pulse 60 to 66. 



Treatment. — The animal was placed in a dark box. Milk, gruel, 

 hay, and oats were offered. Bicarbonate of soda was added to the 

 drinking-water. Five and a half fluid drachms of an emulsion pre- 

 pared from the cerebral substance of a dog was subcutaneously in- 

 jected, and two quantities of two and a half and five fluid drachms of 

 I per cent, iodine solution were injected intra-venously. Though con- 

 tinued from the 6th to the 15th May, this treatment appeared to have 

 no effect on the temperature, circulation, respiration, or on the mus- 

 cular contractions. Nevertheless, during the hour following the iodine 

 injections excitement seemed diminished. 



Next day there was no particular change. The bowels were con- 

 stipated. Passage of urine was frequent and painful. Six and a half 

 ounces of sodium sulphate and four drachms of bicarbonate were added 

 to the drinking-water. 



On the 7th tension about the neck and trismus were less marked. 

 Swallowing was easier. Temperature 38" 1° to 387° C. ; respiration 28 

 to 32 ; pulse 60 to 66, 



On the 8th the improvement continued. Temperature 38° to 

 38*9° C. ; respiration 22 to 30 ; pulse 60 to 62. 



On the 9th condition stationary. The patient moved about its box. 

 The eye was still partly covered by the membrana nictitans. Tem- 

 perature 38° to 38*4° C. ; respiration 25 to 32 ; pulse 60 to 64. 



From the loth to the i8th May the condition was more satis- 

 factory. The symptoms gradually diminished. Temperature 37*9° 

 to 38*6° C. ; respiration 25 to 28 ; pulse 52 to 60. From the 15th only 

 one daily injection of two and a half drachms of iodine solution was 

 made. 



On the 19th May the iodine treatment was stopped. The jaws 

 were moved normally. There was only trifling stiffness when moving. 

 Recovery was assured. The animal left hospital on the 24th. 



Remarks. — None of the drugs, or combination of drugs, yet sug- 

 gested for the treatment of tetanus are of much value. In the horse, 



