542 



CLINICAL VETERINARY MEDICINE AND SURGERY 



Summary of Inoculation Experiments on the Guinea-pig. — In sum- 

 marising the results obtained by inoculating guinea-pigs with avian 

 tuberculosis the animals may conveniently be classified into four 

 groups : — (i) Those in which the autopsy showed no appreciable 

 lesion ; (2) those in which a caseous abscess was found at the point 

 of inoculation; (3) those which showed a few visceral tubercles; and 

 (4) those in which the disease became generalised and revealed itself 

 by an outbreak of tubercles sometimes as abundant as when human 

 tuberculous material is used for inoculation. 



These different results are given in the table hereafter. In each 

 group the animals have been divided into two categories — those which 

 died spontaneously, and those which were killed. In each of these 

 again we have noted how long the animal lived after inoculation. 



Successive Inoculation with Avian and Human Tuberculosis. — We 

 might add to the experiments already described many others consisting 

 of inoculating guinea-pigs with cultures of avian tuberculosis. 

 Certain animals resisted, a fact which enabled us to undertake the 

 study of a fresh problem, viz. whether after such inoculation any modi- 

 fication occurred in the animal's receptivity to human tuberculosis. 



On the 25th March, 1890, we injected a guinea-pig intra-peritone- 

 ally with a certain quantity of avian culture. On the igth October, 



